HitPredict

Interactor 1: MCM5 (P29496)
Minichromosome maintenance protein 5 (EC 3.6.4.12) (Cell division control protein 46)
Gene: MCM5

Interactor 2: MCM7 (P38132)
DNA replication licensing factor MCM7 (EC 3.6.4.12) (Cell division control protein 47) (Minichromosome maintenance protein 7)
Gene: MCM7

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.971

The method score is based on:

Property Details
Experiments 9315644, 16429126, 25313033, 19106085, 25172955, 17895243, 32804080, 35296675, 37968396, 22421151
Identification Methods two hybrid, coimmunoprecipitation, affinity chromatography technology, biochemical, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains MCM~MCM, MCM~MCM_lid, MCM~MCM_N, MCM~MCM_OB, MCM_N~MCM_N, MCM_N~MCM_OB, MCM_OB~MCM_OB
Common GO terms GO:0000727 - double-strand break repair via break-induced replication
GO:0000781 - chromosome, telomeric region
GO:0003682 - chromatin binding
GO:0003688 - DNA replication origin binding
GO:0003697 - single-stranded DNA binding
and 18 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 775
Sc

1 845
+ Hs
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+ Mm
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+ Dm
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+ Dm
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+ Xl
+ Dm
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+ Sc

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Last updated: 15 Jul 2024