HitPredict

Interactor 1: LNX1 (O70263)
E3 ubiquitin-protein ligase LNX (EC 2.3.2.27) (Ligand of Numb protein X 1) (Ligand of Numb-binding protein 1) (Numb-binding protein 1) (RING-type E3 ubiquitin transferase LNX)
Gene: LNX1

Interactor 2: LIPB1 (Q8C8U0)
Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1)
Gene: Ppfibp1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	27889896
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~SAM_1, PDZ~SAM_2
Common GO terms	-
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 728 Mm			1 969
+	Mm
		266780 LNX1_MOUSE (1-728): 1.97e-147: 449: 100.00		KAZRN_MOUSE (154-919): 1.28e-67: 243: 19.47
+	Hs
		1292173 PARD3_HUMAN (233-555): 1.47e-31: 134: 20.50		LIPB1_HUMAN (1-969): 4.38e-153: 480: 85.86
+	Mm
		1230017 LNX2_MOUSE (4-728): 1.48e-113: 360: 45.42		KAZRN_MOUSE (154-919): 1.28e-67: 243: 19.47
+	Mm
		266760 LNX1_MOUSE (1-728): 1.97e-147: 449: 100.00		LIPA3_MOUSE (44-521): 4.95e-12: 72.2: 10.81
+	Mm
		74692 LNX1_MOUSE (1-728): 1.97e-147: 449: 100.00		B2RXW8_MOUSE (18-631): 1.98e-10: 67.2: 9.09
+	Hs
		772915 LNX1_HUMAN (1-728): 1.53e-134: 416: 87.57		MYH9_HUMAN (2-592): 3.1e-20: 99.5: 10.55
+	Mm
		266795 LNX1_MOUSE (1-728): 1.97e-147: 449: 100.00		LIPA2_MOUSE (68-558): 5.98e-10: 65.6: 8.89
+	Mm
		401 LNX1_MOUSE (1-728): 1.97e-147: 449: 100.00		A0A087WPM2_MOUSE (47-515): 3.65e-09: 62.9: 8.72
+	Hs
		271630 LNX1_HUMAN (1-728): 1.53e-134: 416: 87.57		LIPA3_HUMAN (37-411): 7.49e-14: 78.4: 12.18
+	Hs
		1095567 LNX1_HUMAN (1-728): 1.53e-134: 416: 87.57		LIPA1_HUMAN (18-495): 5.24e-09: 62.6: 9.71
+	Rn
		1022037 GRIP1_RAT (227-597): 2.85e-37: 152: 18.35		LIPA3_RAT (44-531): 4.07e-12: 72.6: 11.00
+	Rn
		93158 GRIP1_RAT (227-597): 2.85e-37: 152: 18.35		D3ZZ81_RAT (18-631): 6.31e-10: 65.6: 9.09
+	Rn
		1022038 GRIP1_RAT (227-597): 2.85e-37: 152: 18.35		LIPA4_RAT (90-411): 2.34e-09: 63.7: 9.63
+	Rn
		1362440 GRIP2_RAT (326-720): 8.73e-36: 147: 19.66		LIPA4_RAT (90-411): 2.34e-09: 63.7: 9.63
+	Hs
		1095585 GRIP2_HUMAN (314-495): 7.94e-09: 61.4: 21.13		LIPA1_HUMAN (18-495): 5.24e-09: 62.6: 9.71