Protein: LIPA3
Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3)

Gene: LIPA3, PPFIA3
Organism: Homo sapiens
Interactions: 43
UniProt ID: O75145

Gene Ontology (top 5):
GO:0001669 - acrosomal vesicle
GO:0005829 - cytosol
GO:0007269 - neurotransmitter secretion
GO:0016081 - synaptic vesicle docking
GO:0048172 - regulation of short-term neuronal synaptic plasticity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

271634

ASPP1
Apoptosis-stimulating of p53 protein 1

2

5

High-throughput

0.783

High

271608

LIPA2
Liprin-alpha-2

2

15

Small-scale

0.757

High

271620

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

4

11

High-throughput

0.706

High

271616

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

4

4

High-throughput

0.694

High

271641

GIT1
ARF GTPase-activating protein GIT1

1

7

Small-scale

0.680

High

271619

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

3

11

High-throughput

0.675

High

271622

GPS2
G protein pathway suppressor 2

3

1

High-throughput

0.667

High

271631

R3GEF
Guanine nucleotide exchange factor for Rab-3A

3

0

High-throughput

0.638

High

271607

LIPA3
Liprin-alpha-3

1

14

Small-scale

0.621

High

271614

PTPRD
Receptor-type tyrosine-protein phosphatase delta

1

11

Small-scale

0.621

High

271621

LIPA1
Liprin-alpha-1

1

15

Small-scale

0.621

High

271623

PTPRS
Receptor-type tyrosine-protein phosphatase S

1

11

Small-scale

0.621

High

271628

LIPB1
Liprin-beta-1

1

14

Small-scale

0.621

High

271625

BTNL9
Butyrophilin-like protein 9

1

7

High-throughput

0.618

High

271635

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

7

High-throughput

0.618

High

250185

VINEX
Vinexin

2

8

High-throughput

0.606

High

271638

DISC1
Disrupted in schizophrenia 1 protein

2

1

High-throughput

0.606

High

271633

CNKR1
Connector enhancer of kinase suppressor of ras 1

1

13

Small-scale

0.579

High

271627

RIMS1
Regulating synaptic membrane exocytosis protein 1

1

10

High-throughput

0.575

High

271643

EMIL1
EMILIN-1

2

10

High-throughput

0.574

High

271612

PTPRF
Receptor-type tyrosine-protein phosphatase F

1

11

Small-scale

0.555

High

271630

LNX1
E3 ubiquitin-protein ligase LNX

1

16

Small-scale

0.553

High

271613

TAU
Microtubule-associated protein tau

1

7

High-throughput

0.536

High

271632

BRK1
Protein BRICK1

1

2

High-throughput

0.536

High

177099

ERC2
ERC protein 2

1

17

Small-scale

0.527

High

271626

TPGS1
Tubulin polyglutamylase complex subunit 1

1

1

High-throughput

0.489

High

271637

MED4
Mediator of RNA polymerase II transcription subunit 4

1

1

High-throughput

0.489

High

123525

MYO1C
Unconventional myosin-Ic

1

14

High-throughput

0.479

High

271610

GCR
Glucocorticoid receptor

1

9

High-throughput

0.479

High

271611

HS90B
Heat shock protein HSP 90-beta

1

4

High-throughput

0.479

High

271615

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

9

High-throughput

0.479

High

271624

RN123
E3 ubiquitin-protein ligase RNF123

1

6

High-throughput

0.479

High

271640

BRPF3
Bromodomain and PHD finger-containing protein 3

1

3

High-throughput

0.479

High

271618

S10AA
Protein S100-A10

1

18

High-throughput

0.470

High

254675

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

3

High-throughput

0.445

High

271617

TERA
Transitional endoplasmic reticulum ATPase

1

4

High-throughput

0.445

High

104939

APRIO
Alternative prion protein

1

5

High-throughput

0.437

High

271609

TULP3
Tubby-related protein 3

1

2

High-throughput

0.437

High

271642

TRRAP
Transformation/transcription domain-associated protein

1

2

High-throughput

0.437

High

271629

CBY2
Protein chibby homolog 2

2

0

High-throughput

0.316

High

271639

TFP11
Tuftelin-interacting protein 11

2

0

High-throughput

0.316

High

271636

CF263
Cilia- and flagella-associated protein 263

1

0

High-throughput

0.269

Low


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Last updated: 11Aug2025