HitPredict

Interactor 1: EED (O75530)
Polycomb protein EED (hEED) (Embryonic ectoderm development protein) (WD protein associating with integrin cytoplasmic tails 1) (WAIT-1)
Gene: EED

Interactor 2: SKP1 (P63208)
S-phase kinase-associated protein 1 (Cyclin-A/CDK2-associated protein p19) (p19A) (Organ of Corti protein 2) (OCP-2) (Organ of Corti protein II) (OCP-II) (RNA polymerase II elongation factor-like protein) (SIII) (Transcription elongation factor B polypeptide 1-like) (p19skp1)
Gene: SKP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24457600
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 441 Hs			1 163
+	Mm
		1265636 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		SKP1_MOUSE (1-163): 8.88e-88: 255: 99.39
+	Hs
		245588 TBL1X_HUMAN (13-441): 1.12e-73: 243: 11.39		SKP1_HUMAN (1-163): 1.62e-87: 254: 100.00
+	Mm
		1257397 FBXW7_MOUSE (219-439): 5.6e-28: 118: 15.32		SKP1_MOUSE (1-163): 8.88e-88: 255: 99.39
+	Hs
		929021 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		SKP1_HUMAN (1-163): 1.62e-87: 254: 100.00
+	Dm
		285042 FBXW7_DROME (224-441): 2.22e-25: 111: 15.53		O77430_DROME (1-163): 1.01e-79: 235: 76.69
+	Mm
		1131317 FBW1B_MOUSE (160-352): 1.68e-12: 71.3: 18.97		SKP1_MOUSE (1-163): 8.88e-88: 255: 99.39
+	Hs
		929110 FBW1B_HUMAN (160-352): 1.57e-12: 71.3: 18.97		SKP1_HUMAN (1-163): 1.62e-87: 254: 100.00
+	Ce
		105997 LIN23_CAEEL (160-438): 8.73e-18: 87.9: 20.36		G5EDD8_CAEEL (4-162): 1.84e-65: 199: 60.25