Protein: PRI2
DNA primase large subunit (DNA primase 58 kDa subunit) (p58)

Gene: PRI2, PRIM2
Organism: Homo sapiens
Interactions: 83
UniProt ID: P49643

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0005654 - nucleoplasm
GO:0005658 - alpha DNA polymerase:primase complex
GO:0006269 - DNA replication, synthesis of primer
GO:0006270 - DNA replication initiation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

885522

PRI1
DNA primase small subunit

6

3

Small-scale

0.948

High

487987

DPOLA
DNA polymerase alpha catalytic subunit

2

3

Small-scale

0.755

High

885572

RAE1L
mRNA export factor RAE1

4

1

High-throughput

0.694

High

885600

MMS19
MMS19 nucleotide excision repair protein homolog

5

0

Small-scale

0.676

High

549550

PRPS2
Ribose-phosphate pyrophosphokinase 2

3

1

High-throughput

0.609

High

588192

RFA2
Replication protein A 32 kDa subunit

2

0

Small-scale

0.607

High

885590

P20D2
Xaa-Arg dipeptidase

2

0

High-throughput

0.602

High

302783

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

3

1

Small-scale

0.585

High

885574

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

2

0

High-throughput

0.576

High

885598

RNF31
E3 ubiquitin-protein ligase RNF31

2

1

High-throughput

0.574

High

694915

RFA1
Replication protein A 70 kDa DNA-binding subunit

2

0

Small-scale

0.569

High

303118

RGS20
Regulator of G-protein signaling 20

2

1

High-throughput

0.558

High

885594

NLGNY
Neuroligin-4, Y-linked

2

1

High-throughput

0.558

High

885599

BT3L4
Transcription factor BTF3 homolog 4

2

1

High-throughput

0.549

High

885611

CIA2B
Cytosolic iron-sulfur assembly component 2B

2

0

Small-scale

0.547

High

885582

DCA10
DDB1- and CUL4-associated factor 10

1

1

High-throughput

0.536

High

241081

PRKN
E3 ubiquitin-protein ligase parkin

2

1

High-throughput

0.533

High

158416

RFXK
DNA-binding protein RFXANK

1

0

High-throughput

0.513

High

407600

S100B
Protein S100-B

1

0

High-throughput

0.513

High

856586

BAG6
Large proline-rich protein BAG6

1

0

High-throughput

0.513

High

885573

SSRP1
FACT complex subunit SSRP1

1

0

High-throughput

0.513

High

885589

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

885591

CDK20
Cyclin-dependent kinase 20

1

0

High-throughput

0.513

High

885613

AMMR1
Nuclear protein AMMECR1

1

0

High-throughput

0.513

High

885615

RPC8
DNA-directed RNA polymerase III subunit RPC8

1

0

High-throughput

0.513

High

185523

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

1

High-throughput

0.501

High

885577

DPOA2
DNA polymerase alpha subunit B

1

2

Small-scale

0.501

High

885586

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

0

High-throughput

0.493

High

629658

BTF3
Transcription factor BTF3

1

1

High-throughput

0.489

High

216393

SUV91
Histone-lysine N-methyltransferase SUV39H1

1

0

High-throughput

0.486

High

246482

KDM1A
Lysine-specific histone demethylase 1A

1

0

High-throughput

0.486

High

885595

DCA11
DDB1- and CUL4-associated factor 11

1

1

High-throughput

0.479

High

885597

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

1

High-throughput

0.479

High

885608

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

885584

Q6P9E2
RECK protein

1

1

High-throughput

0.470

High

122732

KIF2A
Kinesin-like protein KIF2A

1

0

High-throughput

0.458

High

259621

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

315282

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

371468

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

567300

TCTP
Translationally-controlled tumor protein

1

0

High-throughput

0.458

High

767687

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

881489

CDK8
Cyclin-dependent kinase 8

1

0

High-throughput

0.458

High

885570

1433Z
14-3-3 protein zeta/delta

1

0

High-throughput

0.458

High

885575

TIF1B
Transcription intermediary factor 1-beta

1

0

High-throughput

0.458

High

885578

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

885580

UB2V2
Ubiquitin-conjugating enzyme E2 variant 2

1

0

High-throughput

0.458

High

885588

UBP37
Ubiquitin carboxyl-terminal hydrolase 37

1

0

Small-scale

0.458

High

885596

FBX32
F-box only protein 32

1

0

High-throughput

0.458

High

885606

STN1
CST complex subunit STN1

1

0

High-throughput

0.458

High

352011

RECK
Reversion-inducing cysteine-rich protein with Kazal motifs

1

1

High-throughput

0.439

High

637002

VATB2
V-type proton ATPase subunit B, brain isoform

1

1

High-throughput

0.437

High

731081

STIP1
Stress-induced-phosphoprotein 1

1

1

High-throughput

0.437

High

885583

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.437

High

885585

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

429522

JUN
Transcription factor Jun

1

0

High-throughput

0.426

High

765250

BMI1
Polycomb complex protein BMI-1

1

0

High-throughput

0.426

High

885603

SYT11
Synaptotagmin-11

1

0

High-throughput

0.426

High

66981

A6NMU8
Neuroligin 4 Y-linked

1

1

High-throughput

0.407

High

75557

B3KSW4
Regulator of G protein signaling 20

1

1

High-throughput

0.407

High

885569

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

1

High-throughput

0.407

High

885610

KLH20
Kelch-like protein 20

3

0

High-throughput

0.347

High

885602

ERP44
Endoplasmic reticulum resident protein 44

2

0

High-throughput

0.328

High

885601

DUS9
Dual specificity protein phosphatase 9

2

0

High-throughput

0.318

High

885609

PNMA2
Paraneoplastic antigen Ma2

2

0

High-throughput

0.313

High

190330

COPT1
High affinity copper uptake protein 1

1

0

High-throughput

0.279

Low

334158

ATG7
Ubiquitin-like modifier-activating enzyme ATG7

1

0

High-throughput

0.279

Low

630225

TNR1B
Tumor necrosis factor receptor superfamily member 1B

1

0

High-throughput

0.279

Low

885587

MILR1
Allergin-1

1

0

High-throughput

0.279

Low

885593

BBS1
BBSome complex member BBS1

1

0

High-throughput

0.279

Low

885604

SHRPN
Sharpin

1

0

High-throughput

0.279

Low

885612

RT18C
Small ribosomal subunit protein bS18m

1

0

High-throughput

0.279

Low

885614

NGN3
Neurogenin-3

1

0

High-throughput

0.279

Low

411576

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

885571

ACTC
Actin, alpha cardiac muscle 1

1

0

High-throughput

0.249

Low

885576

TRI14
Tripartite motif-containing protein 14

1

0

High-throughput

0.249

Low

885605

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

885607

GFOD1
Glucose-fructose oxidoreductase domain-containing protein 1

1

0

High-throughput

0.249

Low

58796

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

0

High-throughput

0.232

Low

391204

FRIL
Ferritin light chain

1

0

High-throughput

0.232

Low

664848

RAE1
Rab proteins geranylgeranyltransferase component A 1

1

0

High-throughput

0.232

Low

885579

NADC
Nicotinate-nucleotide pyrophosphorylase [carboxylating]

1

0

High-throughput

0.232

Low

885581

SPXN3
Sperm protein associated with the nucleus on the X chromosome N3

1

0

High-throughput

0.232

Low

885592

LYPD1
Ly6/PLAUR domain-containing protein 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025