HitPredict

Interactor 1: EED (O75530)
Polycomb protein EED (hEED) (Embryonic ectoderm development protein) (WD protein associating with integrin cytoplasmic tails 1) (WAIT-1)
Gene: EED

Interactor 2: Q15156 (Q15156)
PML-RAR protein
Gene: PML-RAR

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	17560333
Identification Methods	anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 441 Hs			1 797
+	Hs
		267939 EED_HUMAN (1-441): 2.11e-92: 287: 100.00		HNF4A_HUMAN (384-797): 7.78e-106: 335: 23.29
+	Hs
		245573 TBL1X_HUMAN (13-441): 1.12e-73: 243: 11.39		PPARG_HUMAN (378-751): 2.01e-120: 374: 30.02
+	Mm
		1142707 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		ERR2_MOUSE (405-752): 2.18e-90: 293: 29.02
+	Hs
		245574 TBL1X_HUMAN (13-441): 1.12e-73: 243: 11.39		HNF4A_HUMAN (384-797): 7.78e-106: 335: 23.29
+	Hs
		740596 TBL1R_HUMAN (4-335): 2.6e-56: 195: 11.40		PPARG_HUMAN (378-751): 2.01e-120: 374: 30.02
+	Hs
		268200 EED_HUMAN (1-441): 2.11e-92: 287: 100.00		ESR2_HUMAN (343-781): 1.46e-84: 280: 22.83
+	Hs
		488022 TBL1R_HUMAN (4-335): 2.6e-56: 195: 11.40		RARA_HUMAN (350-797): 2.03e-106: 336: 90.40
+	Hs
		245556 TBL1X_HUMAN (13-441): 1.12e-73: 243: 11.39		THB_HUMAN (353-751): 4.43e-87: 285: 32.24
+	Hs
		370377 TBL1R_HUMAN (4-335): 2.6e-56: 195: 11.40		ESR1_HUMAN (336-795): 6.4e-97: 315: 20.89
+	Hs
		500505 TBL1R_HUMAN (4-335): 2.6e-56: 195: 11.40		THB_HUMAN (353-751): 4.43e-87: 285: 32.24
+	Hs
		1269548 TBL1R_HUMAN (4-335): 2.6e-56: 195: 11.40		ESR2_HUMAN (343-781): 1.46e-84: 280: 22.83
+	Hs
		245555 TBL1X_HUMAN (13-441): 1.12e-73: 243: 11.39		THA_HUMAN (423-727): 9.32e-60: 212: 37.46
+	Hs
		488008 SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29		RARA_HUMAN (350-797): 2.03e-106: 336: 90.40
+	Hs
		668886 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		PML_HUMAN (1-413): 7.06e-89: 301: 96.37
+	Hs
		369932 WDR5B_HUMAN (279-439): 2.9e-21: 96.1: 12.27		ESR1_HUMAN (336-795): 6.4e-97: 315: 20.89
+	Hs
		500446 TBL1R_HUMAN (4-335): 2.6e-56: 195: 11.40		THA_HUMAN (423-727): 9.32e-60: 212: 37.46
+	Hs
		370309 TBL1Y_HUMAN (277-439): 5.06e-19: 91.1: 13.33		ESR1_HUMAN (336-795): 6.4e-97: 315: 20.89
+	Hs
		668898 SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29		PML_HUMAN (1-413): 7.06e-89: 301: 96.37
+	Xl
		546250 TB1RA_XENLA (279-439): 2.07e-18: 89.2: 14.11		THAA_XENLA (363-754): 1.8e-87: 284: 34.45
+	Hs
		1269467 TBL1Y_HUMAN (277-439): 5.06e-19: 91.1: 13.33		ESR2_HUMAN (343-781): 1.46e-84: 280: 22.83