HitPredict

Interactor 1: DAB1 (O75553)
Disabled homolog 1
Gene: DAB1

Interactor 2: NCK1 (P16333)
SH2/SH3 adapter protein NCK1 (Cytoplasmic protein NCK1) (NCK adapter protein 1) (Nck-1) (SH2/SH3 adapter protein NCK-alpha)
Gene: NCK1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	14517291
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 588 Hs			1 377
+	Mm
		956235 DAB1_MOUSE (1-588): 3.86e-74: 249: 91.50		NCK1_MOUSE (1-377): 7.48e-99: 300: 98.94
+	Hs
		208964 DAB1_HUMAN (1-588): 2.31e-74: 250: 100.00		NCK2_HUMAN (1-376): 7.1e-90: 277: 68.24
+	Mm
		223010 DAB1_MOUSE (1-588): 3.86e-74: 249: 91.50		NCK2_MOUSE (1-376): 3.75e-90: 277: 66.93
+	Hs
		557659 DAB2_HUMAN (8-587): 2.74e-41: 161: 23.98		NCK1_HUMAN (1-377): 1.69e-98: 299: 100.00
+	Hs
		209098 ANS1B_HUMAN (9-229): 2.08e-44: 171: 17.70		NCK2_HUMAN (1-376): 7.1e-90: 277: 68.24
+	Mm
		763385 DAB1_MOUSE (1-588): 3.86e-74: 249: 91.50		FYN_MOUSE (7-173): 7.13e-21: 96: 15.39
+	Mm
		956225 DAB1_MOUSE (1-588): 3.86e-74: 249: 91.50		YES_MOUSE (5-201): 6.24e-20: 93.2: 16.42
+	Hs
		269148 DAB1_HUMAN (1-588): 2.31e-74: 250: 100.00		ITSN1_HUMAN (5-286): 1.55e-16: 83.6: 17.07
+	Mm
		403429 DAB1_MOUSE (1-588): 3.86e-74: 249: 91.50		SRC_MOUSE (5-114): 1.55e-15: 79.7: 22.32
+	Hs
		269176 DAB1_HUMAN (1-588): 2.31e-74: 250: 100.00		SH3K1_HUMAN (58-207): 2.14e-09: 61.3: 17.76
+	Hs
		655317 DAB2_HUMAN (8-587): 2.74e-41: 161: 23.98		P85A_HUMAN (241-376): 1.37e-22: 101: 19.57
+	Hs
		412132 DAB2_HUMAN (8-587): 2.74e-41: 161: 23.98		FYN_HUMAN (7-173): 7.47e-21: 96: 15.39
+	Hs
		454823 DAB2_HUMAN (8-587): 2.74e-41: 161: 23.98		FGR_HUMAN (7-150): 8.06e-20: 92.9: 20.00
+	Mm
		957157 DAB2_MOUSE (8-587): 1.14e-43: 168: 23.51		ITSN1_MOUSE (5-286): 2.38e-17: 85.9: 17.19
+	Mm
		1206702 ANS1B_MOUSE (9-236): 2.44e-42: 165: 15.95		ITSN1_MOUSE (5-286): 2.38e-17: 85.9: 17.19
+	Mm
		957139 DAB2_MOUSE (8-587): 1.14e-43: 168: 23.51		GRB2_MOUSE (1-61): 1.55e-16: 79.4: 29.03
+	Hs
		957186 DAB2_HUMAN (8-587): 2.74e-41: 161: 23.98		ITSN1_HUMAN (5-286): 1.55e-16: 83.6: 17.07
+	Hs
		522909 DAB2_HUMAN (8-587): 2.74e-41: 161: 23.98		SRC_HUMAN (5-114): 1.61e-15: 79.7: 22.32
+	Hs
		924477 DAB2_HUMAN (8-587): 2.74e-41: 161: 23.98		GRB2_HUMAN (3-61): 2.12e-16: 79.1: 28.81
+	Hs
		782772 DAB2_HUMAN (8-587): 2.74e-41: 161: 23.98		CSK_HUMAN (4-143): 1.92e-12: 70.2: 14.38