HitPredict

Interactor 1: DAB1 (O75553)
Disabled homolog 1
Gene: DAB1

Interactor 2: CRK (P46108)
Adapter molecule crk (Proto-oncogene c-Crk) (p38)
Gene: CRK

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	15316068
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001764 - neuron migration GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016358 - dendrite development GO:0021766 - hippocampus development
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 588 Hs			1 304
+	Mm
		956229 DAB1_MOUSE (1-588): 3.86e-74: 249: 91.50		CRK_MOUSE (1-304): 5.53e-68: 215: 99.67
+	Hs
		269125 DAB1_HUMAN (1-588): 2.31e-74: 250: 100.00		CRKL_HUMAN (2-302): 4.5e-57: 187: 48.07
+	Mm
		815088 DAB1_MOUSE (1-588): 3.86e-74: 249: 91.50		CRKL_MOUSE (2-302): 6.92e-57: 187: 47.10
+	Mm
		956228 DAB1_MOUSE (1-588): 3.86e-74: 249: 91.50		PLCG1_MOUSE (2-302): 1.1e-26: 112: 15.43
+	Hs
		208964 DAB1_HUMAN (1-588): 2.31e-74: 250: 100.00		NCK2_HUMAN (2-100): 3.06e-11: 65.2: 18.00
+	Mm
		223010 DAB1_MOUSE (1-588): 3.86e-74: 249: 91.50		NCK2_MOUSE (59-195): 2.76e-11: 65.3: 20.55
+	Hs
		269120 DAB1_HUMAN (1-588): 2.31e-74: 250: 100.00		NCK1_HUMAN (2-100): 1.55e-10: 63.3: 18.00
+	Hs
		269148 DAB1_HUMAN (1-588): 2.31e-74: 250: 100.00		ITSN1_HUMAN (150-302): 3.02e-10: 63.3: 13.87
+	Hs
		269176 DAB1_HUMAN (1-588): 2.31e-74: 250: 100.00		SH3K1_HUMAN (114-192): 4.08e-10: 62.5: 22.22
+	Mm
		956235 DAB1_MOUSE (1-588): 3.86e-74: 249: 91.50		NCK1_MOUSE (2-100): 1.35e-10: 63.3: 18.00
+	Mm
		957139 DAB2_MOUSE (8-587): 1.14e-43: 168: 23.51		GRB2_MOUSE (135-297): 1.43e-25: 103: 15.67
+	Hs
		924477 DAB2_HUMAN (8-587): 2.74e-41: 161: 23.98		GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67
+	Ce
		1353620 NUMB1_CAEEL (28-294): 6.55e-51: 186: 19.34		Q9U2T9_CAEEL (182-300): 9.9e-11: 64.7: 13.22
+	Mm
		957157 DAB2_MOUSE (8-587): 1.14e-43: 168: 23.51		ITSN1_MOUSE (143-302): 6.55e-13: 71.4: 10.98
+	Hs
		1191815 ANS1B_HUMAN (9-229): 2.08e-44: 171: 17.70		CD2AP_HUMAN (1-196): 4.74e-12: 68.3: 17.12
+	Mm
		1206702 ANS1B_MOUSE (9-236): 2.44e-42: 165: 15.95		ITSN1_MOUSE (143-302): 6.55e-13: 71.4: 10.98
+	Hs
		209098 ANS1B_HUMAN (9-229): 2.08e-44: 171: 17.70		NCK2_HUMAN (2-100): 3.06e-11: 65.2: 18.00
+	Mm
		957150 DAB2_MOUSE (8-587): 1.14e-43: 168: 23.51		SH3K1_MOUSE (114-186): 2.23e-10: 63.3: 21.33
+	Hs
		557659 DAB2_HUMAN (8-587): 2.74e-41: 161: 23.98		NCK1_HUMAN (2-100): 1.55e-10: 63.3: 18.00
+	Hs
		957186 DAB2_HUMAN (8-587): 2.74e-41: 161: 23.98		ITSN1_HUMAN (150-302): 3.02e-10: 63.3: 13.87