HitPredict

Interactor 1: PRKRA (O75569)
Interferon-inducible double-stranded RNA-dependent protein kinase activator A (PKR-associated protein X) (PKR-associating protein X) (Protein activator of the interferon-induced protein kinase) (Protein kinase, interferon-inducible double-stranded RNA-dependent activator)
Gene: PRKRA

Interactor 2: MYCN (P04198)
N-myc proto-oncogene protein (Class E basic helix-loop-helix protein 37) (bHLHe37)
Gene: MYCN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35013218
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 313 Hs			1 464
+	Hs
		269596 PRKRA_HUMAN (1-313): 1.21e-119: 348: 100.00		MYC_HUMAN (7-463): 5.91e-69: 228: 34.16
+	Hs
		379442 TRBP2_HUMAN (18-313): 1.34e-81: 253: 41.08		MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00
+	Hs
		346871 TRBP2_HUMAN (18-313): 1.34e-81: 253: 41.08		MYC_HUMAN (7-463): 5.91e-69: 228: 34.16
+	Hs
		379344 ILF3_HUMAN (7-290): 1.14e-53: 190: 13.71		MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00
+	Hs
		379006 E2AK2_HUMAN (36-311): 2.71e-51: 179: 18.50		MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00
+	Hs
		379662 DGCR8_HUMAN (1-276): 1.44e-44: 163: 19.42		MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00
+	Hs
		346654 ILF3_HUMAN (7-290): 1.14e-53: 190: 13.71		MYC_HUMAN (7-463): 5.91e-69: 228: 34.16
+	Hs
		345898 E2AK2_HUMAN (36-311): 2.71e-51: 179: 18.50		MYC_HUMAN (7-463): 5.91e-69: 228: 34.16
+	Hs
		379759 STRBP_HUMAN (5-176): 5.53e-30: 121: 15.09		MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00
+	Hs
		379923 STAU2_HUMAN (33-309): 3.5e-30: 121: 18.79		MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00
+	Hs
		379169 DSRAD_HUMAN (90-306): 2.7e-29: 120: 16.51		MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00
+	Hs
		347454 DGCR8_HUMAN (1-276): 1.44e-44: 163: 19.42		MYC_HUMAN (7-463): 5.91e-69: 228: 34.16
+	Hs
		379272 RED1_HUMAN (228-306): 5.95e-12: 68.4: 16.46		MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00
+	Hs
		347663 STRBP_HUMAN (5-176): 5.53e-30: 121: 15.09		MYC_HUMAN (7-463): 5.91e-69: 228: 34.16
+	Hs
		348014 STAU2_HUMAN (33-309): 3.5e-30: 121: 18.79		MYC_HUMAN (7-463): 5.91e-69: 228: 34.16
+	Hs
		346338 DSRAD_HUMAN (90-306): 2.7e-29: 120: 16.51		MYC_HUMAN (7-463): 5.91e-69: 228: 34.16
+	Hs
		322057 STAU1_HUMAN (82-309): 9.84e-10: 61.5: 17.54		MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00
+	Hs
		322048 STAU1_HUMAN (82-309): 9.84e-10: 61.5: 17.54		MYC_HUMAN (7-463): 5.91e-69: 228: 34.16