Protein: RHG17
Rho GTPase-activating protein 17 (Rho-type GTPase-activating protein 17) (RhoGAP interacting with CIP4 homologs protein 1) (RICH-1)

Gene: RHG17, ARHGAP17
Organism: Homo sapiens
Interactions: 69
UniProt ID: Q68EM7

Gene Ontology (top 5):
GO:0005096 - GTPase activator activity
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0005923 - bicellular tight junction
GO:0007165 - signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1165233

RHG44
Rho GTPase-activating protein 44

5

13

High-throughput

0.929

High

1150865

CIP4
Cdc42-interacting protein 4

4

18

Small-scale

0.915

High

1229263

3BP1
SH3 domain-binding protein 1

3

13

High-throughput

0.871

High

1229264

CD2AP
CD2-associated protein

3

20

Small-scale

0.817

High

1229251

DLG3
Disks large homolog 3

2

5

High-throughput

0.776

High

955287

CDC42
Cell division control protein 42 homolog

2

20

Small-scale

0.768

High

1229253

SH3K1
SH3 domain-containing kinase-binding protein 1

7

20

Small-scale

0.741

High

1229256

PACN1
Protein kinase C and casein kinase substrate in neurons protein 1

3

19

Small-scale

0.658

High

1229242

DNMBP
Dynamin-binding protein

1

17

High-throughput

0.656

High

362308

ABL1
Tyrosine-protein kinase ABL1

1

20

Small-scale

0.647

High

440117

LCK
Tyrosine-protein kinase Lck

1

20

Small-scale

0.647

High

557346

SRC
Proto-oncogene tyrosine-protein kinase Src

1

20

Small-scale

0.647

High

699777

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

17

Small-scale

0.647

High

855645

CRK
Adapter molecule crk

1

20

Small-scale

0.647

High

987703

GRB2
Growth factor receptor-bound protein 2

1

20

Small-scale

0.647

High

988442

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

Small-scale

0.647

High

1054119

BTK
Tyrosine-protein kinase BTK

1

20

Small-scale

0.647

High

1229254

FNBP1
Formin-binding protein 1

1

18

Small-scale

0.647

High

1229262

SHLB1
Endophilin-B1

1

19

Small-scale

0.647

High

1196991

AMOT
Angiomotin

2

9

Small-scale

0.639

High

1060527

KLC1
Kinesin light chain 1

2

2

High-throughput

0.628

High

952891

ACTB
Actin, cytoplasmic 1

1

16

High-throughput

0.618

High

978083

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.618

High

1212223

NHRF3
Na(+)/H(+) exchange regulatory cofactor NHE-RF3

2

20

High-throughput

0.611

High

1150436

NHRF2
Na(+)/H(+) exchange regulatory cofactor NHE-RF2

2

18

High-throughput

0.601

High

867205

CAPZB
F-actin-capping protein subunit beta

2

2

Small-scale

0.584

High

1229244

CF337
Cilia- and flagella-associated protein 337

2

8

High-throughput

0.567

High

162842

NHRF1
Na(+)/H(+) exchange regulatory cofactor NHE-RF1

2

18

Small-scale

0.565

High

347105

BAG2
BAG family molecular chaperone regulator 2

1

4

High-throughput

0.536

High

613369

VINC
Vinculin

1

8

High-throughput

0.536

High

732627

ARRB2
Beta-arrestin-2

1

3

High-throughput

0.536

High

966459

1433G
14-3-3 protein gamma

1

20

High-throughput

0.536

High

1049413

1433F
14-3-3 protein eta

1

20

High-throughput

0.536

High

1229239

TRI68
E3 ubiquitin-protein ligase TRIM68

1

4

High-throughput

0.536

High

1229245

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

2

High-throughput

0.536

High

1229259

EIF3K
Eukaryotic translation initiation factor 3 subunit K

1

0

High-throughput

0.513

High

422312

A4
Amyloid-beta precursor protein

1

4

High-throughput

0.501

High

1124621

SRC8
Src substrate cortactin

1

20

Small-scale

0.501

High

706164

S10A2
Protein S100-A2

1

9

High-throughput

0.489

High

848652

MAGA9
Melanoma-associated antigen 9

1

7

High-throughput

0.489

High

325883

UBR5
E3 ubiquitin-protein ligase UBR5

1

7

High-throughput

0.479

High

337595

FMNL1
Formin-like protein 1

1

5

Small-scale

0.479

High

412088

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.479

High

459636

PROF1
Profilin-1

1

9

High-throughput

0.479

High

553210

KCRB
Creatine kinase B-type

1

2

High-throughput

0.479

High

835692

KPCI
Protein kinase C iota type

1

2

Small-scale

0.479

High

915110

CAZA1
F-actin-capping protein subunit alpha-1

1

6

Small-scale

0.479

High

934737

TERA
Transitional endoplasmic reticulum ATPase

1

2

High-throughput

0.479

High

1033020

EWS
RNA-binding protein EWS

1

3

High-throughput

0.479

High

1152107

MARE1
Microtubule-associated protein RP/EB family member 1

1

5

High-throughput

0.479

High

1229240

LTOR1
Ragulator complex protein LAMTOR1

1

1

High-throughput

0.479

High

1229246

PALS1
Protein PALS1

1

5

Small-scale

0.479

High

1229248

INADL
InaD-like protein

1

14

Small-scale

0.479

High

1229250

PARD3
Partitioning defective 3 homolog

1

18

Small-scale

0.479

High

1229257

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.479

High

1229258

PAR6A
Partitioning defective 6 homolog alpha

1

6

Small-scale

0.479

High

1229260

ZO2
Tight junction protein 2

1

10

High-throughput

0.479

High

1229261

LSM2
U6 snRNA-associated Sm-like protein LSm2

1

4

High-throughput

0.479

High

897860

CDK9
Cyclin-dependent kinase 9

1

3

High-throughput

0.470

High

227587

SPOP
Speckle-type POZ protein

1

2

High-throughput

0.437

High

695700

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

9

High-throughput

0.437

High

768417

RFA3
Replication protein A 14 kDa subunit

1

6

High-throughput

0.437

High

1229241

FBX42
F-box only protein 42

1

4

High-throughput

0.437

High

1229243

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.437

High

1229249

CE192
Centrosomal protein of 192 kDa

1

0

High-throughput

0.426

High

71057

PDZ1P
Putative PDZ domain-containing protein PDZK1P1

1

20

High-throughput

0.407

High

1229247

GLT16
Polypeptide N-acetylgalactosaminyltransferase 16

2

0

High-throughput

0.328

High

1229255

NIPS1
Protein NipSnap homolog 1

2

0

High-throughput

0.298

High

1229252

NXPE3
NXPE family member 3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025