HitPredict

Interactor 1: PRKRA (O75569)
Interferon-inducible double-stranded RNA-dependent protein kinase activator A (PKR-associated protein X) (PKR-associating protein X) (Protein activator of the interferon-induced protein kinase) (Protein kinase, interferon-inducible double-stranded RNA-dependent activator)
Gene: PRKRA

Interactor 2: PK1IP (Q9NWT1)
p21-activated protein kinase-interacting protein 1 (PAK/PLC-interacting protein 1) (hPIP1) (PAK1-interacting protein 1) (WD repeat-containing protein 84)
Gene: PAK1IP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 313 Hs			1 392
+	Hs
		269942 PRKRA_HUMAN (1-313): 1.21e-119: 348: 100.00		FBW1A_HUMAN (2-286): 6.86e-64: 216: 16.72
+	Hs
		269908 PRKRA_HUMAN (1-313): 1.21e-119: 348: 100.00		NLE1_HUMAN (154-389): 4e-38: 144: 10.04
+	Hs
		269670 PRKRA_HUMAN (1-313): 1.21e-119: 348: 100.00		WDR5_HUMAN (202-377): 2.11e-30: 120: 13.66
+	Hs
		269826 PRKRA_HUMAN (1-313): 1.21e-119: 348: 100.00		FBXW7_HUMAN (1-146): 6.23e-26: 111: 19.48
+	Hs
		1264674 DGCR8_HUMAN (1-276): 1.44e-44: 163: 19.42		PK1IP_HUMAN (1-392): 6.72e-91: 280: 100.00
+	Hs
		1020008 ILF3_HUMAN (7-290): 1.14e-53: 190: 13.71		FBW1A_HUMAN (2-286): 6.86e-64: 216: 16.72
+	Hs
		1019991 ILF3_HUMAN (7-290): 1.14e-53: 190: 13.71		FBW1B_HUMAN (3-231): 7.86e-44: 161: 16.87
+	Hs
		877396 DSRAD_HUMAN (90-306): 2.7e-29: 120: 16.51		FBW1A_HUMAN (2-286): 6.86e-64: 216: 16.72
+	Hs
		903179 ILF3_HUMAN (7-290): 1.14e-53: 190: 13.71		WDR5_HUMAN (202-377): 2.11e-30: 120: 13.66
+	Hs
		585518 E2AK2_HUMAN (36-311): 2.71e-51: 179: 18.50		FBXW7_HUMAN (1-146): 6.23e-26: 111: 19.48
+	Hs
		877384 DSRAD_HUMAN (90-306): 2.7e-29: 120: 16.51		FBW1B_HUMAN (3-231): 7.86e-44: 161: 16.87
+	Hs
		1019876 ILF3_HUMAN (7-290): 1.14e-53: 190: 13.71		SNR40_HUMAN (237-391): 4.8e-13: 71.8: 9.62
+	Hs
		877337 DSRAD_HUMAN (90-306): 2.7e-29: 120: 16.51		FBXW7_HUMAN (1-146): 6.23e-26: 111: 19.48
+	Hs
		944964 RED1_HUMAN (228-306): 5.95e-12: 68.4: 16.46		NLE1_HUMAN (154-389): 4e-38: 144: 10.04
+	Hs
		323214 STAU1_HUMAN (82-309): 9.84e-10: 61.5: 17.54		NLE1_HUMAN (154-389): 4e-38: 144: 10.04
+	Hs
		1288255 STRBP_HUMAN (5-176): 5.53e-30: 121: 15.09		SNR40_HUMAN (237-391): 4.8e-13: 71.8: 9.62
+	Mm
		1112923 DSRAD_MOUSE (169-313): 2.13e-10: 63.8: 15.48		FBW1A_MOUSE (3-172): 2.59e-29: 121: 20.11
+	Hs
		322417 STAU1_HUMAN (82-309): 9.84e-10: 61.5: 17.54		WDR5_HUMAN (202-377): 2.11e-30: 120: 13.66