HitPredict

Interactor 1: PRKRA (O75569)
Interferon-inducible double-stranded RNA-dependent protein kinase activator A (PKR-associated protein X) (PKR-associating protein X) (Protein activator of the interferon-induced protein kinase) (Protein kinase, interferon-inducible double-stranded RNA-dependent activator)
Gene: PRKRA

Interactor 2: HECD1 (Q9ULT8)
E3 ubiquitin-protein ligase HECTD1 (EC 2.3.2.26) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1)
Gene: HECTD1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35915203
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 313 Hs			1 2610
+	Hs
		1075649 TRBP2_HUMAN (18-313): 1.34e-81: 253: 41.08		HECD1_HUMAN (1-2610): 0: 2419: 100.00
+	Hs
		585584 E2AK2_HUMAN (36-311): 2.71e-51: 179: 18.50		HECD1_HUMAN (1-2610): 0: 2419: 100.00
+	Hs
		1264691 DGCR8_HUMAN (1-276): 1.44e-44: 163: 19.42		HECD1_HUMAN (1-2610): 0: 2419: 100.00
+	Hs
		1302244 STRBP_HUMAN (5-176): 5.53e-30: 121: 15.09		HECD1_HUMAN (1-2610): 0: 2419: 100.00
+	Hs
		1346011 STAU2_HUMAN (33-309): 3.5e-30: 121: 18.79		HECD1_HUMAN (1-2610): 0: 2419: 100.00
+	Hs
		877389 DSRAD_HUMAN (90-306): 2.7e-29: 120: 16.51		HECD1_HUMAN (1-2610): 0: 2419: 100.00
+	Hs
		323296 STAU1_HUMAN (82-309): 9.84e-10: 61.5: 17.54		HECD1_HUMAN (1-2610): 0: 2419: 100.00
+	Hs
		125047 PRKRA_HUMAN (1-313): 1.21e-119: 348: 100.00		WWP2_HUMAN (2265-2608): 1.64e-107: 368: 24.86
+	Hs
		1075625 TRBP2_HUMAN (18-313): 1.34e-81: 253: 41.08		NED4L_HUMAN (2255-2608): 4.26e-117: 399: 21.67
+	Hs
		585577 E2AK2_HUMAN (36-311): 2.71e-51: 179: 18.50		HECW2_HUMAN (1360-2609): 2.26e-127: 444: 14.40
+	Hs
		269733 PRKRA_HUMAN (1-313): 1.21e-119: 348: 100.00		TRIPC_HUMAN (5-1083): 4.48e-58: 225: 14.03
+	Hs
		125420 ILF3_HUMAN (7-290): 1.14e-53: 190: 13.71		WWP2_HUMAN (2265-2608): 1.64e-107: 368: 24.86
+	Hs
		125604 DGCR8_HUMAN (1-276): 1.44e-44: 163: 19.42		WWP2_HUMAN (2265-2608): 1.64e-107: 368: 24.86
+	Hs
		877365 DSRAD_HUMAN (90-306): 2.7e-29: 120: 16.51		SMUF2_HUMAN (2235-2607): 4.78e-118: 395: 20.62
+	Hs
		125743 STAU2_HUMAN (33-309): 3.5e-30: 121: 18.79		WWP2_HUMAN (2265-2608): 1.64e-107: 368: 24.86
+	Hs
		125365 RED1_HUMAN (228-306): 5.95e-12: 68.4: 16.46		WWP2_HUMAN (2265-2608): 1.64e-107: 368: 24.86
+	Hs
		125069 STAU1_HUMAN (82-309): 9.84e-10: 61.5: 17.54		WWP2_HUMAN (2265-2608): 1.64e-107: 368: 24.86
+	Hs
		1019742 ILF3_HUMAN (7-290): 1.14e-53: 190: 13.71		TRIPC_HUMAN (5-1083): 4.48e-58: 225: 14.03
+	Hs
		322628 STAU1_HUMAN (82-309): 9.84e-10: 61.5: 17.54		TRIPC_HUMAN (5-1083): 4.48e-58: 225: 14.03
+	Hs
		585503 E2AK2_HUMAN (36-311): 2.71e-51: 179: 18.50		HACE1_HUMAN (204-449): 1.11e-20: 102: 14.96