HitPredict

Interactor 1: LRP6 (O75581)
Low-density lipoprotein receptor-related protein 6 (LRP-6)
Gene: LRP6

Interactor 2: ZNRF3 (Q9ULT6)
E3 ubiquitin-protein ligase ZNRF3 (EC 2.3.2.27) (RING finger protein 203) (RING-type E3 ubiquitin transferase ZNRF3) (Zinc/RING finger protein 3)
Gene: ZNRF3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 0.55 0.576

The method score is based on:

Property Details
Experiments 36131013, 22575959
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005109 - frizzled binding
GO:0005886 - plasma membrane
GO:0016055 - Wnt signaling pathway
Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024