HitPredict

Interactor 1: NPM3 (O75607)
Nucleoplasmin-3
Gene: NPM3

Interactor 2: BRX1 (Q8TDN6)
Ribosome biogenesis protein BRX1 homolog (Brix domain-containing protein 2)
Gene: BRIX1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	24981860, 33961781
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005730 - nucleolus GO:0006364 - rRNA processing
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 178 Hs			1 353
+	Hs
		418486 NPM_HUMAN (30-175): 2.57e-47: 157: 38.67		BRX1_HUMAN (1-353): 6.13e-146: 418: 100.00
+	Hs
		271419 NPM3_HUMAN (11-178): 4.49e-81: 239: 100.00		RPF1_HUMAN (13-269): 1.37e-72: 230: 20.83
+	Hs
		418544 NPM_HUMAN (30-175): 2.57e-47: 157: 38.67		IMP4_HUMAN (2-272): 6.92e-91: 275: 17.56
+	Hs
		418680 NPM_HUMAN (30-175): 2.57e-47: 157: 38.67		RPF1_HUMAN (13-269): 1.37e-72: 230: 20.83
+	Hs
		271417 NPM3_HUMAN (11-178): 4.49e-81: 239: 100.00		RPF2_HUMAN (106-247): 1.01e-31: 122: 22.88
+	Hs
		271425 NPM3_HUMAN (11-178): 4.49e-81: 239: 100.00		SSF1_HUMAN (54-228): 2.87e-21: 96.4: 15.22
+	Hs
		418670 NPM_HUMAN (30-175): 2.57e-47: 157: 38.67		RPF2_HUMAN (106-247): 1.01e-31: 122: 22.88
+	Hs
		418697 NPM_HUMAN (30-175): 2.57e-47: 157: 38.67		SSF1_HUMAN (54-228): 2.87e-21: 96.4: 15.22