HitPredict

Interactor 1: SPB7 (O75635)
Serpin B7 (Megsin) (TP55)
Gene: SERPINB7

Interactor 2: RENR (O75787)
Renin receptor (ATPase H(+)-transporting lysosomal accessory protein 2) (ATPase H(+)-transporting lysosomal-interacting protein 2) (ER-localized type I transmembrane adapter) (Embryonic liver differentiation factor 10) (N14F) (Renin/prorenin receptor) (Vacuolar ATP synthase membrane sector-associated protein M8-9) (ATP6M8-9) (V-ATPase M8.9 subunit) [Cleaved into: Renin receptor N-terminal fragment; Renin receptor C-terminal fragment]
Gene: ATP6AP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0032914 - positive regulation of transforming growth factor beta1 production
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 380 Hs			1 350
+	Hs
		275133 SPB13_HUMAN (1-380): 2.3e-156: 446: 37.50		RENR_HUMAN (1-350): 1.38e-167: 472: 100.00
+	Hs
		274964 SPB8_HUMAN (1-380): 2.22e-155: 443: 36.10		RENR_HUMAN (1-350): 1.38e-167: 472: 100.00
+	Hs
		274959 SPB4_HUMAN (1-380): 1.4e-153: 440: 39.80		RENR_HUMAN (1-350): 1.38e-167: 472: 100.00
+	Hs
		274941 SPB3_HUMAN (1-380): 6.18e-151: 433: 39.80		RENR_HUMAN (1-350): 1.38e-167: 472: 100.00
+	Hs
		274889 AACT_HUMAN (4-380): 1.07e-146: 423: 31.07		RENR_HUMAN (1-350): 1.38e-167: 472: 100.00
+	Hs
		275051 SPA12_HUMAN (4-380): 4.77e-132: 386: 27.11		RENR_HUMAN (1-350): 1.38e-167: 472: 100.00