HitPredict

Interactor 1: S2512 (O75746)
Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial (Araceli hiperlarga) (Aralar) (Aralar1) (Mitochondrial aspartate glutamate carrier 1) (Solute carrier family 25 member 12)
Gene: SLC25A12

Interactor 2: S2513 (Q9UJS0)
Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial (Calcium-binding mitochondrial carrier protein Aralar2) (ARALAR-related gene 2) (ARALAR2) (Citrin) (Mitochondrial aspartate glutamate carrier 2) (Solute carrier family 25 member 13)
Gene: SLC25A13

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.78	1.00	0.887

The method score is based on:

Property	Details
Experiments	28514442, 33961781, 32877691, 34349018
Identification Methods	affinity chromatography technology, proximity labelling technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	Mito_carr~Mito_carr
Common GO terms	GO:0000514 - 3-sulfino-L-alanine: proton, glutamate antiporter activity GO:0000515 - aspartate:glutamate, proton antiporter activity GO:0005313 - L-glutamate transmembrane transporter activity GO:0005509 - calcium ion binding GO:0005739 - mitochondrion and 9 others more... GO:0005743 - mitochondrial inner membrane GO:0006094 - gluconeogenesis GO:0009066 - aspartate family amino acid metabolic process GO:0015172 - acidic amino acid transmembrane transporter activity GO:0015183 - L-aspartate transmembrane transporter activity GO:0015810 - aspartate transmembrane transport GO:0015813 - L-glutamate transmembrane transport GO:0043490 - malate-aspartate shuttle GO:0051592 - response to calcium ion
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1	678
Hs

1	675

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024