HitPredict

Interactor 1: RENR (O75787)
Renin receptor (ATPase H(+)-transporting lysosomal accessory protein 2) (ATPase H(+)-transporting lysosomal-interacting protein 2) (ER-localized type I transmembrane adapter) (Embryonic liver differentiation factor 10) (N14F) (Renin/prorenin receptor) (Vacuolar ATP synthase membrane sector-associated protein M8-9) (ATP6M8-9) (V-ATPase M8.9 subunit) [Cleaved into: Renin receptor N-terminal fragment; Renin receptor C-terminal fragment]
Gene: ATP6AP2

Interactor 2: S10A8 (P05109)
Protein S100-A8 (Calgranulin-A) (Calprotectin L1L subunit) (Cystic fibrosis antigen) (CFAG) (Leukocyte L1 complex light chain) (Migration inhibitory factor-related protein 8) (MRP-8) (p8) (S100 calcium-binding protein A8) (Urinary stone protein band A)
Gene: S100A8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 350 Hs			1 93
+	Hs
		274936 RENR_HUMAN (1-350): 1.38e-167: 472: 100.00		S100P_HUMAN (2-92): 1.25e-30: 105: 35.79
+	Hs
		275022 RENR_HUMAN (1-350): 1.38e-167: 472: 100.00		FILA2_HUMAN (2-89): 4.61e-25: 99.1: 29.35
+	Hs
		274929 RENR_HUMAN (1-350): 1.38e-167: 472: 100.00		FILA_HUMAN (2-90): 4.67e-19: 81.8: 27.96
+	Hs
		275041 RENR_HUMAN (1-350): 1.38e-167: 472: 100.00		S1A7A_HUMAN (3-91): 1.56e-17: 72.5: 24.21