HitPredict

Interactor 1: NIPS2 (O75323)
Protein NipSnap homolog 2 (NipSnap2) (Glioblastoma-amplified sequence)
Gene: NIPSNAP2

Interactor 2: MLP3B (Q9GZQ8)
Microtubule-associated protein 1 light chain 3 beta (Autophagy-related protein LC3 B) (Autophagy-related ubiquitin-like modifier LC3 B) (MAP1 light chain 3-like protein 2) (Microtubule-associated proteins 1A/1B light chain 3B) (MAP1A/MAP1B LC3 B) (MAP1A/MAP1B light chain 3 B)
Gene: MAP1LC3B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.639

Property	Details
Experiments	31006538, 20562859
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000423 - mitophagy GO:0005739 - mitochondrion
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 286 Hs			1 125
+	Hs
		1409589 NIPS1_HUMAN (1-286): 3.14e-155: 436: 68.18		MLP3B_HUMAN (1-125): 8.31e-57: 173: 100.00
+	Hs
		276176 NIPS2_HUMAN (1-286): 1.62e-156: 439: 100.00		MLP3A_HUMAN (1-120): 8.25e-55: 168: 82.50
+	Hs
		1409596 NIPS1_HUMAN (1-286): 3.14e-155: 436: 68.18		MLP3A_HUMAN (1-120): 8.25e-55: 168: 82.50
+	Hs
		276096 NIPS2_HUMAN (1-286): 1.62e-156: 439: 100.00		GBRL2_HUMAN (7-120): 2.22e-53: 165: 39.47
+	Hs
		276025 NIPS2_HUMAN (1-286): 1.62e-156: 439: 100.00		GBRAP_HUMAN (7-121): 6.43e-53: 163: 31.30
+	Hs
		952313 NIPS1_HUMAN (1-286): 3.14e-155: 436: 68.18		GBRL2_HUMAN (7-120): 2.22e-53: 165: 39.47
+	Hs
		276171 NIPS2_HUMAN (1-286): 1.62e-156: 439: 100.00		MLP3C_HUMAN (1-120): 2.09e-51: 161: 55.00
+	Hs
		276174 NIPS2_HUMAN (1-286): 1.62e-156: 439: 100.00		GBRL1_HUMAN (7-120): 1.51e-51: 160: 32.46
+	Hs
		328128 NIPS1_HUMAN (1-286): 3.14e-155: 436: 68.18		GBRAP_HUMAN (7-121): 6.43e-53: 163: 31.30
+	Hs
		1409592 NIPS1_HUMAN (1-286): 3.14e-155: 436: 68.18		GBRL1_HUMAN (7-120): 1.51e-51: 160: 32.46