HitPredict

Interactor 1: STAM2 (O75886)
Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein)
Gene: STAM2

Interactor 2: EPHA6 (Q9UF33)
Ephrin type-A receptor 6 (EC 2.7.10.1) (EPH homology kinase 2) (EHK-2) (EPH-like kinase 12) (EK12)
Gene: EPHA6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.646

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~SH3_1
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 525 Hs			1 1036
+	Hs
		277067 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		EPHA7_HUMAN (9-1036): 0: 1192: 55.53
+	Hs
		277036 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		EPHA5_HUMAN (11-1028): 0: 1177: 56.86
+	Hs
		277037 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		EPHA4_HUMAN (15-1036): 0: 1176: 56.88
+	Hs
		277011 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		EPHA3_HUMAN (24-1028): 0: 1168: 59.56
+	Hs
		872470 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		EPHA5_HUMAN (11-1028): 0: 1177: 56.86
+	Hs
		277012 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		EPHA8_HUMAN (34-1036): 0: 1095: 52.45
+	Hs
		277010 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		EPHA2_HUMAN (6-1036): 0: 1046: 45.57
+	Hs
		665508 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		EPHA8_HUMAN (34-1036): 0: 1095: 52.45
+	Hs
		665303 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		EPHA2_HUMAN (6-1036): 0: 1046: 45.57
+	Hs
		277004 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		FGFR3_HUMAN (221-960): 3.46e-178: 541: 20.51
+	Hs
		277002 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		FGFR2_HUMAN (251-982): 2.91e-159: 492: 20.41
+	Hs
		276996 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		FGFR1_HUMAN (329-968): 6.7e-154: 478: 19.36
+	Hs
		609455 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		FGFR3_HUMAN (221-960): 3.46e-178: 541: 20.51
+	Hs
		601561 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		FGFR2_HUMAN (251-982): 2.91e-159: 492: 20.41
+	Hs
		508131 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		FGFR1_HUMAN (329-968): 6.7e-154: 478: 19.36
+	Hs
		508257 GGA1_HUMAN (2-516): 8.21e-63: 218: 14.50		FGFR1_HUMAN (329-968): 6.7e-154: 478: 19.36
+	Hs
		508231 GGA3_HUMAN (1-510): 1.35e-56: 203: 15.73		FGFR1_HUMAN (329-968): 6.7e-154: 478: 19.36
+	Hs
		435783 GGA3_HUMAN (1-510): 1.35e-56: 203: 15.73		IGF1R_HUMAN (388-932): 8.62e-131: 431: 26.92
+	Hs
		272786 TM1L1_HUMAN (6-494): 3.07e-63: 215: 16.02		FYN_HUMAN (625-931): 3.77e-59: 214: 37.99
+	Hs
		272790 TM1L1_HUMAN (6-494): 3.07e-63: 215: 16.02		SRC_HUMAN (623-931): 3.42e-59: 214: 40.32