Protein: ZN536
Zinc finger protein 536

Gene: ZN536, ZNF536
Organism: Homo sapiens
Interactions: 68
UniProt ID: O15090

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

177450

KLF3
Krueppel-like factor 3

2

20

High-throughput

0.754

High

177460

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

4

High-throughput

0.691

High

177445

SOX2
Transcription factor SOX-2

3

10

Small-scale

0.656

High

177430

EGR2
E3 SUMO-protein ligase EGR2

1

15

High-throughput

0.618

High

177433

EGR1
Early growth response protein 1

1

14

High-throughput

0.618

High

177470

SP7
Transcription factor Sp7

1

20

High-throughput

0.618

High

177486

KLF12
Krueppel-like factor 12

1

20

High-throughput

0.618

High

177458

HDAC1
Histone deacetylase 1

2

10

High-throughput

0.584

High

177461

NFIX
Nuclear factor 1 X-type

2

17

High-throughput

0.584

High

177424

S100B
Protein S100-B

1

2

High-throughput

0.536

High

177463

TEAD2
Transcriptional enhancer factor TEF-4

1

3

High-throughput

0.536

High

177474

FOXC2
Forkhead box protein C2

1

3

High-throughput

0.536

High

177478

FOXJ2
Forkhead box protein J2

1

4

High-throughput

0.536

High

177432

H15
Histone H1.5

1

6

High-throughput

0.515

High

177452

H11
Histone H1.1

1

5

High-throughput

0.515

High

177479

DBNL
Drebrin-like protein

1

1

High-throughput

0.489

High

142716

NFIB
Nuclear factor 1 B-type

1

17

High-throughput

0.479

High

177420

TBXT
T-box transcription factor T

1

3

High-throughput

0.479

High

177421

CRX
Cone-rod homeobox protein

1

7

High-throughput

0.479

High

177422

MYC
Myc proto-oncogene protein

1

3

High-throughput

0.479

High

177423

GCR
Glucocorticoid receptor

1

18

High-throughput

0.479

High

177426

NFIC
Nuclear factor 1 C-type

1

17

High-throughput

0.479

High

177429

MYB
Transcriptional activator Myb

1

1

High-throughput

0.479

High

177431

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

177434

SP100
Nuclear autoantigen Sp-100

1

7

High-throughput

0.479

High

177435

GATA2
Endothelial transcription factor GATA-2

1

5

High-throughput

0.479

High

177436

GATA3
Trans-acting T-cell-specific transcription factor GATA-3

1

5

High-throughput

0.479

High

177437

PAX6
Paired box protein Pax-6

1

5

High-throughput

0.479

High

177438

APEX1
DNA repair nuclease/redox regulator APEX1

1

2

High-throughput

0.479

High

177439

TEAD1
Transcriptional enhancer factor TEF-1

1

3

High-throughput

0.479

High

177440

TLX1
T-cell leukemia homeobox protein 1

1

12

High-throughput

0.479

High

177441

HNF1B
Hepatocyte nuclear factor 1-beta

1

7

High-throughput

0.479

High

177442

PPARG
Peroxisome proliferator-activated receptor gamma

1

16

High-throughput

0.479

High

177443

COIL
Coilin

1

3

High-throughput

0.479

High

177446

CENPA
Histone H3-like centromeric protein A

1

10

High-throughput

0.479

High

177447

LHX2
LIM/homeobox protein Lhx2

1

6

High-throughput

0.479

High

177448

PAX9
Paired box protein Pax-9

1

4

High-throughput

0.479

High

177449

GSC
Homeobox protein goosecoid

1

6

High-throughput

0.479

High

177453

HME1
Homeobox protein engrailed-1

1

5

High-throughput

0.479

High

177455

NFIA
Nuclear factor 1 A-type

1

17

High-throughput

0.479

High

177456

FOXI1
Forkhead box protein I1

1

3

High-throughput

0.479

High

177457

FOXL1
Forkhead box protein L1

1

3

High-throughput

0.479

High

177459

CUL3
Cullin-3

1

20

High-throughput

0.479

High

177462

EEA1
Early endosome antigen 1

1

4

High-throughput

0.479

High

177464

TBR1
T-box brain protein 1

1

3

High-throughput

0.479

High

177467

FBX38
F-box only protein 38

1

1

High-throughput

0.479

High

177471

PHIP
PH-interacting protein

1

2

High-throughput

0.479

High

177472

PF21A
PHD finger protein 21A

1

17

High-throughput

0.479

High

177475

GCM1
Chorion-specific transcription factor GCMa

1

1

High-throughput

0.479

High

177481

RCOR1
REST corepressor 1

1

12

High-throughput

0.479

High

177482

LHX6
LIM/homeobox protein Lhx6

1

5

High-throughput

0.479

High

177483

ASF1A
Histone chaperone ASF1A

1

1

High-throughput

0.479

High

177485

ZN330
Zinc finger protein 330

1

2

High-throughput

0.479

High

177425

IF2A
Eukaryotic translation initiation factor 2 subunit 1

1

0

High-throughput

0.458

High

177451

ARP3
Actin-related protein 3

1

0

High-throughput

0.458

High

177473

MMS19
MMS19 nucleotide excision repair protein homolog

1

0

High-throughput

0.458

High

177477

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

177484

CIA2B
Cytosolic iron-sulfur assembly component 2B

1

0

High-throughput

0.458

High

177427

CALM2
Calmodulin-2

1

1

High-throughput

0.445

High

177428

CALM3
Calmodulin-3

1

1

High-throughput

0.445

High

177454

GOGA2
Golgin subfamily A member 2

1

6

High-throughput

0.437

High

177466

KLH22
Kelch-like protein 22

1

0

High-throughput

0.426

High

177444

EAA1
Excitatory amino acid transporter 1

1

1

High-throughput

0.407

High

177465

S39AC
Zinc transporter ZIP12

1

2

High-throughput

0.407

High

177468

CCD71
Coiled-coil domain-containing protein 71

1

0

Small-scale

0.249

Low

177469

DHX40
Probable ATP-dependent RNA helicase DHX40

1

0

High-throughput

0.249

Low

177476

S22AB
Solute carrier family 22 member 11

1

0

High-throughput

0.232

Low

177480

GGA2
ADP-ribosylation factor-binding protein GGA2

1

0

High-throughput

0.213

Low


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Last updated: 11Aug2025