HitPredict

Interactor 1: STAM2 (O75886)
Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein)
Gene: STAM2

Interactor 2: UBQL2 (Q9UHD9)
Ubiquilin-2 (Chap1) (DSK2 homolog) (Protein linking IAP with cytoskeleton 2) (PLIC-2) (hPLIC-2) (Ubiquitin-like product Chap1/Dsk2)
Gene: UBQLN2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	1.00	0.843

Property	Details
Experiments	32296183, 33277362, unassigned1304
Identification Methods	two hybrid, affinity chromatography technology, validated two hybrid, two hybrid array, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	SH3_1~ubiquitin, UIM~ubiquitin, VHS~ubiquitin
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 525 Hs			1 624
+	Hs
		277154 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		UBQL1_HUMAN (1-624): 8.68e-147: 439: 71.52
+	Hs
		1270627 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		UBQL2_HUMAN (1-624): 1.19e-153: 458: 100.00
+	Hs
		277139 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		UBQL4_HUMAN (22-624): 2.17e-124: 382: 54.55
+	Hs
		1173032 TM1L2_HUMAN (1-466): 2.13e-88: 282: 17.19		UBQL2_HUMAN (1-624): 1.19e-153: 458: 100.00
+	Hs
		272826 TM1L1_HUMAN (6-494): 3.07e-63: 215: 16.02		UBQL2_HUMAN (1-624): 1.19e-153: 458: 100.00
+	Hs
		1355398 GGA2_HUMAN (2-511): 3.8e-55: 197: 16.80		UBQL2_HUMAN (1-624): 1.19e-153: 458: 100.00
+	Hs
		1045562 SPTN1_HUMAN (103-481): 2.5e-55: 202: 14.59		UBQL1_HUMAN (1-624): 8.68e-147: 439: 71.52
+	Hs
		1078927 ITSN1_HUMAN (188-414): 1.91e-46: 176: 22.50		UBQL2_HUMAN (1-624): 1.19e-153: 458: 100.00
+	Hs
		160220 HGS_HUMAN (135-518): 7.87e-15: 79.4: 10.95		UBQL2_HUMAN (1-624): 1.19e-153: 458: 100.00
+	Hs
		924926 GRB2_HUMAN (207-262): 4.5e-12: 67.4: 52.63		UBQL2_HUMAN (1-624): 1.19e-153: 458: 100.00
+	Hs
		160228 HGS_HUMAN (135-518): 7.87e-15: 79.4: 10.95		UBQL1_HUMAN (1-624): 8.68e-147: 439: 71.52
+	Hs
		277047 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		RS27A_HUMAN (33-119): 4.49e-24: 100: 27.27
+	Hs
		160203 HGS_HUMAN (135-518): 7.87e-15: 79.4: 10.95		UBQL4_HUMAN (22-624): 2.17e-124: 382: 54.55
+	Hs
		924099 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		RS27A_HUMAN (33-119): 4.49e-24: 100: 27.27
+	Hs
		160088 HGS_HUMAN (135-518): 7.87e-15: 79.4: 10.95		UBQLN_HUMAN (5-445): 3.18e-75: 249: 33.00
+	Hs
		924264 GRB2_HUMAN (207-262): 4.5e-12: 67.4: 52.63		RL40_HUMAN (33-112): 7.49e-34: 127: 30.86
+	Hs
		923946 GRB2_HUMAN (207-262): 4.5e-12: 67.4: 52.63		RS27A_HUMAN (33-119): 4.49e-24: 100: 27.27