HitPredict

Interactor 1: DGAT1 (O75907)
Diacylglycerol O-acyltransferase 1 (EC 2.3.1.20) (ACAT-related gene product 1) (Acyl-CoA retinol O-fatty-acyltransferase) (ARAT) (Retinol O-fatty-acyltransferase) (EC 2.3.1.76) (Diglyceride acyltransferase)
Gene: DGAT1

Interactor 2: C3AR (Q16581)
C3a anaphylatoxin chemotactic receptor (C3AR) (C3a-R)
Gene: C3AR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0035579 - specific granule membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 488 Hs			1 482
+	Hs
		277437 DGAT1_HUMAN (1-488): 0: 604: 100.00		CXCR4_HUMAN (322-457): 2.26e-36: 139: 23.78
+	Hs
		277451 DGAT1_HUMAN (1-488): 0: 604: 100.00		CML1_HUMAN (289-479): 4.78e-27: 113: 28.71
+	Hs
		277436 DGAT1_HUMAN (1-488): 0: 604: 100.00		CCR9_HUMAN (323-453): 1.12e-23: 103: 22.06
+	Hs
		277439 DGAT1_HUMAN (1-488): 0: 604: 100.00		GPR17_HUMAN (337-450): 2.07e-17: 85.4: 23.33