HitPredict

Interactor 1: PRAF3 (O75915)
PRA1 family protein 3 (ADP-ribosylation factor-like protein 6-interacting protein 5) (ARL-6-interacting protein 5) (Aip-5) (Cytoskeleton-related vitamin A-responsive protein) (Dermal papilla-derived protein 11) (GTRAP3-18) (Glutamate transporter EAAC1-interacting protein) (JM5) (Prenylated Rab acceptor protein 2) (Protein JWa) (Putative MAPK-activating protein PM27)
Gene: ARL6IP5

Interactor 2: REEP5 (Q00765)
Receptor expression-enhancing protein 5 (Polyposis locus protein 1) (Protein TB2)
Gene: REEP5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	34079125, 33961781
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 188 Hs			1 189
+	Hs
		242243 PRAF2_HUMAN (2-175): 3.94e-69: 209: 45.40		REEP5_HUMAN (1-189): 3.52e-89: 261: 100.00
+	Mm
		1247007 PRAF3_MOUSE (1-188): 2.35e-84: 248: 90.43		REEP3_MOUSE (54-176): 4.15e-45: 151: 29.27
+	Hs
		961877 PRAF1_HUMAN (1-139): 1.68e-35: 124: 21.68		REEP5_HUMAN (1-189): 3.52e-89: 261: 100.00
+	Hs
		242289 PRAF2_HUMAN (2-175): 3.94e-69: 209: 45.40		REEP4_HUMAN (56-177): 2.22e-49: 162: 36.07
+	Hs
		1310096 PRAF1_HUMAN (1-139): 1.68e-35: 124: 21.68		REEP2_HUMAN (54-176): 1.22e-48: 160: 34.15
+	Dm
		52861 A1Z823_DROME (8-155): 2.13e-10: 58.9: 18.24		A1Z9M2_DROME (4-163): 1.81e-68: 208: 47.83
+	Dm
		52864 A1Z823_DROME (8-155): 2.13e-10: 58.9: 18.24		F2FB55_DROME (32-163): 1.93e-57: 179: 52.27
+	Dm
		52889 A1Z823_DROME (8-155): 2.13e-10: 58.9: 18.24		Q9W1J5_DROME (50-182): 4.19e-37: 131: 25.37