HitPredict

Interactor 1: PRAF3 (O75915)
PRA1 family protein 3 (ADP-ribosylation factor-like protein 6-interacting protein 5) (ARL-6-interacting protein 5) (Aip-5) (Cytoskeleton-related vitamin A-responsive protein) (Dermal papilla-derived protein 11) (GTRAP3-18) (Glutamate transporter EAAC1-interacting protein) (JM5) (Prenylated Rab acceptor protein 2) (Protein JWa) (Putative MAPK-activating protein PM27)
Gene: ARL6IP5

Interactor 2: P2Y12 (Q9H244)
P2Y purinoceptor 12 (P2Y12) (ADP-glucose receptor) (ADPG-R) (P2T(AC)) (P2Y(AC)) (P2Y(cyc)) (P2Y12 platelet ADP receptor) (P2Y(ADP)) (SP1999)
Gene: P2RY12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26186194, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 188 Hs			1 342
+	Hs
		277673 PRAF3_HUMAN (1-188): 9.94e-86: 252: 100.00		CCR5_HUMAN (22-320): 3.23e-89: 273: 24.92
+	Hs
		277666 PRAF3_HUMAN (1-188): 9.94e-86: 252: 100.00		LPAR6_HUMAN (13-310): 6.58e-88: 269: 26.49
+	Hs
		242235 PRAF2_HUMAN (2-175): 3.94e-69: 209: 45.40		CCR5_HUMAN (22-320): 3.23e-89: 273: 24.92
+	Hs
		277663 PRAF3_HUMAN (1-188): 9.94e-86: 252: 100.00		CCR2_HUMAN (22-322): 3.34e-64: 209: 22.85