HitPredict

Interactor 1: VAMP4 (O75379)
Vesicle-associated membrane protein 4 (VAMP-4)
Gene: VAMP4

Interactor 2: RASN (P01111)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: NRAS

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30194290
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000139 - Golgi membrane GO:0005794 - Golgi apparatus GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 141 Hs			1 189
+	Hs
		278466 VAMP4_HUMAN (1-120): 6.5e-39: 129: 100.00		RASK_HUMAN (16-189): 7.11e-85: 249: 85.71
+	Hs
		278502 VAMP4_HUMAN (1-120): 6.5e-39: 129: 100.00		RAB35_HUMAN (4-171): 6.54e-84: 247: 34.71
+	Hs
		375308 VAMP7_HUMAN (15-139): 5e-34: 119: 27.20		RASK_HUMAN (16-189): 7.11e-85: 249: 85.71
+	Hs
		908010 VAMP7_HUMAN (15-139): 5e-34: 119: 27.20		RAB35_HUMAN (4-171): 6.54e-84: 247: 34.71
+	Hs
		373850 VAMP7_HUMAN (15-139): 5e-34: 119: 27.20		RASN_HUMAN (1-189): 1.05e-80: 239: 100.00
+	Hs
		278488 VAMP4_HUMAN (1-120): 6.5e-39: 129: 100.00		RB11A_HUMAN (4-184): 8.81e-75: 225: 33.88
+	Hs
		374483 VAMP7_HUMAN (15-139): 5e-34: 119: 27.20		RASH_HUMAN (16-188): 6.69e-79: 234: 84.39
+	Hs
		278486 VAMP4_HUMAN (1-120): 6.5e-39: 129: 100.00		RAB2A_HUMAN (4-185): 5.47e-74: 223: 31.52
+	Hs
		375553 VAMP3_HUMAN (47-119): 1.51e-26: 97: 41.10		RASK_HUMAN (16-189): 7.11e-85: 249: 85.71
+	Hs
		375898 VAMP8_HUMAN (41-120): 1.92e-26: 97: 27.50		RASK_HUMAN (16-189): 7.11e-85: 249: 85.71
+	Hs
		955934 VAMP3_HUMAN (47-119): 1.51e-26: 97: 41.10		RAB8A_HUMAN (4-185): 1.75e-84: 249: 36.02
+	Hs
		907998 VAMP7_HUMAN (15-139): 5e-34: 119: 27.20		RB11A_HUMAN (4-184): 8.81e-75: 225: 33.88
+	Hs
		907994 VAMP7_HUMAN (15-139): 5e-34: 119: 27.20		RAB2A_HUMAN (4-185): 5.47e-74: 223: 31.52
+	Hs
		907995 VAMP7_HUMAN (15-139): 5e-34: 119: 27.20		RAB14_HUMAN (4-185): 1.88e-73: 222: 29.35
+	Hs
		373946 VAMP3_HUMAN (47-119): 1.51e-26: 97: 41.10		RASN_HUMAN (1-189): 1.05e-80: 239: 100.00
+	Hs
		374170 VAMP8_HUMAN (41-120): 1.92e-26: 97: 27.50		RASN_HUMAN (1-189): 1.05e-80: 239: 100.00
+	Hs
		374622 VAMP3_HUMAN (47-119): 1.51e-26: 97: 41.10		RASH_HUMAN (16-188): 6.69e-79: 234: 84.39
+	Hs
		374890 VAMP8_HUMAN (41-120): 1.92e-26: 97: 27.50		RASH_HUMAN (16-188): 6.69e-79: 234: 84.39
+	Hs
		976525 VAMP8_HUMAN (41-120): 1.92e-26: 97: 27.50		RB11A_HUMAN (4-184): 8.81e-75: 225: 33.88
+	Hs
		1155382 VAMP8_HUMAN (41-120): 1.92e-26: 97: 27.50		RB11B_HUMAN (4-184): 1.56e-73: 222: 32.79