Interactor 1: SPF27 (O75934)
Pre-mRNA-splicing factor SPF27 (Breast carcinoma-amplified sequence 2) (DNA amplified in mammary carcinoma 1 protein) (Spliceosome-associated protein SPF 27)
Gene: BCAS2
Interactor 2: PRP19 (Q9UMS4)
Pre-mRNA-processing factor 19 (EC 2.3.2.27) (Nuclear matrix protein 200) (PRP19/PSO4 homolog) (hPso4) (RING-type E3 ubiquitin transferase PRP19) (Senescence evasion factor)
Gene: PRPF19
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.95 | 1.00 | 0.979 |
The method score is based on:
Property | Details |
---|---|
Experiments | 28514442, 29395067, 32460013, 35271311, 20176811, 22365833, 33961781, 24443570, 21536736 |
Identification Methods | affinity chromatography technology, proximity labelling technology, far western blotting, two hybrid, biochemical, pull down, anti tag coimmunoprecipitation |
Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | BCAS2~Prp19, BCAS2~U-box |
Common GO terms | GO:0000398 - mRNA splicing, via spliceosome GO:0000974 - Prp19 complex GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005681 - spliceosomal complex and 3 others more... |
Homologous interactions | 8 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024