Interactor 1: SPF27 (O75934)
Pre-mRNA-splicing factor SPF27 (Breast carcinoma-amplified sequence 2) (DNA amplified in mammary carcinoma 1 protein) (Spliceosome-associated protein SPF 27)
Gene: BCAS2

Interactor 2: PRP19 (Q9UMS4)
Pre-mRNA-processing factor 19 (EC 2.3.2.27) (Nuclear matrix protein 200) (PRP19/PSO4 homolog) (hPso4) (RING-type E3 ubiquitin transferase PRP19) (Senescence evasion factor)
Gene: PRPF19

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.979

The method score is based on:

Property Details
Experiments 28514442, 29395067, 32460013, 35271311, 20176811, 22365833, 33961781, 24443570, 21536736
Identification Methods affinity chromatography technology, proximity labelling technology, far western blotting, two hybrid, biochemical, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains BCAS2~Prp19, BCAS2~U-box
Common GO terms GO:0000398 - mRNA splicing, via spliceosome
GO:0000974 - Prp19 complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005681 - spliceosomal complex
and 3 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 225
Hs

1 504
+ Hs
+ Hs
+ Sp
+ Hs
+ Dm
+ At
+ At
+ At

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Last updated: 15 Jul 2024