HitPredict

Interactor 1: MPDZ (O75970)
Multiple PDZ domain protein (Multi-PDZ domain protein 1)
Gene: MPDZ

Interactor 2: LATS2 (Q9NRM7)
Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Kinase phosphorylated during mitosis protein) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Warts-like kinase)
Gene: LATS2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.50	0.470

Property	Details
Experiments	24255178
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2070 Hs			1 1088
+	Hs
		280011 MPDZ_HUMAN (1-2070): 0: 1287: 100.00		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		1232910 LNX2_HUMAN (490-1086): 3.87e-26: 118: 13.72		LATS2_HUMAN (1-1088): 0: 983: 100.00
+	Hs
		1300675 MAGI1_HUMAN (1658-2069): 1.07e-23: 112: 16.64		LATS2_HUMAN (1-1088): 0: 983: 100.00
+	Hs
		1344984 GRIP1_HUMAN (5-671): 8.64e-22: 105: 12.20		LATS2_HUMAN (1-1088): 0: 983: 100.00
+	Hs
		1020225 PTN13_HUMAN (5-702): 1.45e-20: 102: 11.67		LATS2_HUMAN (1-1088): 0: 983: 100.00
+	Hs
		1246440 INADL_HUMAN (1922-2068): 4.04e-20: 100: 30.00		LATS2_HUMAN (1-1088): 0: 983: 100.00
+	Hs
		325772 MAGI3_HUMAN (1157-2070): 7.64e-34: 145: 15.10		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		325859 MAGI1_HUMAN (1658-2069): 1.07e-23: 112: 16.64		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		325709 PTN13_HUMAN (5-702): 1.45e-20: 102: 11.67		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		325820 INADL_HUMAN (1922-2068): 4.04e-20: 100: 30.00		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		681891 NHRF3_HUMAN (928-1286): 8.93e-33: 137: 17.21		AKT1_HUMAN (532-1043): 2.2e-141: 435: 22.16
+	Mm
		554913 DLG4_MOUSE (649-788): 2.87e-17: 90.5: 29.79		KPCE_MOUSE (554-1010): 2.84e-130: 415: 29.92
+	Mm
		933108 DLG4_MOUSE (649-788): 2.87e-17: 90.5: 29.79		KAPCB_MOUSE (638-1022): 3.87e-133: 409: 31.62
+	Hs
		1073434 MAGI3_HUMAN (1157-2070): 7.64e-34: 145: 15.10		KS6A1_HUMAN (519-977): 1.47e-79: 277: 20.34
+	Hs
		1073433 NHRF3_HUMAN (928-1286): 8.93e-33: 137: 17.21		KS6A1_HUMAN (519-977): 1.47e-79: 277: 20.34
+	Hs
		1073444 MAGI2_HUMAN (73-1158): 8.22e-26: 119: 10.36		KS6A1_HUMAN (519-977): 1.47e-79: 277: 20.34
+	Hs
		1073470 MAGI1_HUMAN (1658-2069): 1.07e-23: 112: 16.64		KS6A1_HUMAN (519-977): 1.47e-79: 277: 20.34
+	Hs
		1073453 LNX1_HUMAN (782-1270): 1.19e-20: 101: 12.63		KS6A1_HUMAN (519-977): 1.47e-79: 277: 20.34
+	Mm
		1143553 DLG4_MOUSE (649-788): 2.87e-17: 90.5: 29.79		KS6A2_MOUSE (519-973): 2.65e-79: 277: 19.79
+	Mm
		936586 DLG4_MOUSE (649-788): 2.87e-17: 90.5: 29.79		ROCK2_MOUSE (640-1008): 1.72e-66: 247: 37.17