HitPredict

Interactor 1: KRT36 (O76013)
Keratin, type I cuticular Ha6 (Hair keratin, type I Ha6) (Keratin-36) (K36)
Gene: KRT36

Interactor 2: KRT83 (P78385)
Keratin, type II cuticular Hb3 (Hair keratin K2.10) (Keratin-83) (K83) (Type II hair keratin Hb3) (Type-II keratin Kb23)
Gene: KRT83

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	36949045
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Filament~Filament
Common GO terms	GO:0005829 - cytosol GO:0030280 - structural constituent of skin epidermis GO:0045095 - keratin filament GO:0045109 - intermediate filament organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 467 Hs			1 493
+	Hs
		359297 K1C14_HUMAN (4-466): 4.36e-147: 429: 49.90		K2C3_HUMAN (83-427): 6.22e-161: 471: 57.02
+	Hs
		444534 K1C17_HUMAN (85-465): 6.17e-149: 433: 56.69		K2C7_HUMAN (27-433): 1.98e-161: 467: 53.30
+	Hs
		380597 K1C17_HUMAN (85-465): 6.17e-149: 433: 56.69		K2C1_HUMAN (80-436): 1.01e-124: 379: 54.60
+	Hs
		359288 K1C14_HUMAN (4-466): 4.36e-147: 429: 49.90		K2C1_HUMAN (80-436): 1.01e-124: 379: 54.60
+	Hs
		359348 K1C14_HUMAN (4-466): 4.36e-147: 429: 49.90		KRT81_HUMAN (7-482): 4.9e-116: 352: 96.01
+	Hs
		409054 K1C17_HUMAN (85-465): 6.17e-149: 433: 56.69		K2C8_HUMAN (83-438): 8.25e-114: 346: 58.15
+	Hs
		359290 K1C14_HUMAN (4-466): 4.36e-147: 429: 49.90		K2C8_HUMAN (83-438): 8.25e-114: 346: 58.15
+	Hs
		213924 K1C14_HUMAN (4-466): 4.36e-147: 429: 49.90		KRT86_HUMAN (1-486): 1e-111: 341: 90.14
+	Hs
		359330 K1C14_HUMAN (4-466): 4.36e-147: 429: 49.90		KRT85_HUMAN (1-479): 1.25e-102: 318: 80.69
+	Hs
		980271 K1C17_HUMAN (85-465): 6.17e-149: 433: 56.69		K2C79_HUMAN (10-433): 4.45e-81: 263: 46.03
+	Hs
		318773 K1C13_HUMAN (82-444): 9.39e-143: 418: 53.30		K2C75_HUMAN (1-425): 2e-85: 275: 47.53
+	Hs
		359368 K1C14_HUMAN (4-466): 4.36e-147: 429: 49.90		K2C79_HUMAN (10-433): 4.45e-81: 263: 46.03
+	Hs
		980257 K1C17_HUMAN (85-465): 6.17e-149: 433: 56.69		K2C72_HUMAN (26-492): 6.58e-79: 257: 43.50
+	Hs
		359351 K1C14_HUMAN (4-466): 4.36e-147: 429: 49.90		K2C72_HUMAN (26-492): 6.58e-79: 257: 43.50
+	Hs
		531555 K1C17_HUMAN (85-465): 6.17e-149: 433: 56.69		K2C5_HUMAN (76-425): 1.12e-73: 245: 58.81
+	Hs
		821648 K1C17_HUMAN (85-465): 6.17e-149: 433: 56.69		K2C6C_HUMAN (76-425): 1.76e-73: 244: 57.67
+	Hs
		359482 K1C17_HUMAN (85-465): 6.17e-149: 433: 56.69		K2C6A_HUMAN (76-425): 1.19e-72: 242: 57.96
+	Hs
		359299 K1C14_HUMAN (4-466): 4.36e-147: 429: 49.90		K2C5_HUMAN (76-425): 1.12e-73: 245: 58.81
+	Hs
		359315 K1C14_HUMAN (4-466): 4.36e-147: 429: 49.90		K2C6C_HUMAN (76-425): 1.76e-73: 244: 57.67
+	Hs
		359460 K1C13_HUMAN (82-444): 9.39e-143: 418: 53.30		K2C6A_HUMAN (76-425): 1.19e-72: 242: 57.96