HitPredict

Interactor 1: RNF8 (O76064)
E3 ubiquitin-protein ligase RNF8 (hRNF8) (EC 2.3.2.27) (RING finger protein 8) (RING-type E3 ubiquitin transferase RNF8)
Gene: RNF8

Interactor 2: RNF8 (O76064)
E3 ubiquitin-protein ligase RNF8 (hRNF8) (EC 2.3.2.27) (RING finger protein 8) (RING-type E3 ubiquitin transferase RNF8)
Gene: RNF8

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 1.00 0.943

The method score is based on:

Property Details
Experiments 28525740, 11322894, 32296183, 22266820, unassigned1304, 22980979
Identification Methods enzymatic study, two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid, x ray scattering
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains FHA~FHA, zf-C3HC4_3~zf-C3HC4_3
Common GO terms GO:0000151 - ubiquitin ligase complex
GO:0000781 - chromosome, telomeric region
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 30 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 485
Hs

1 485
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024