HitPredict

Interactor 1: CIAO1 (O76071)
Probable cytosolic iron-sulfur protein assembly protein CIAO1 (WD repeat-containing protein 39)
Gene: CIAO1

Interactor 2: PKHA5 (Q9HAU0)
Pleckstrin homology domain-containing family A member 5 (PH domain-containing family A member 5) (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2)
Gene: PLEKHA5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	23891004
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~WD40
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 339 Hs			1 1116
+	Hs
		282925 CIAO1_HUMAN (1-337): 6.29e-105: 312: 100.00		PKHA7_HUMAN (2-1059): 8.31e-125: 412: 27.32
+	Hs
		1240465 POC1A_HUMAN (4-91): 1.02e-15: 79.4: 26.14		PKHA5_HUMAN (1-1116): 0: 609: 100.00
+	Hs
		1153371 TBL1R_HUMAN (3-283): 1.27e-63: 211: 25.52		PKHA7_HUMAN (2-1059): 8.31e-125: 412: 27.32
+	Hs
		1153322 FBXW7_HUMAN (3-217): 6.6e-46: 167: 19.73		PKHA7_HUMAN (2-1059): 8.31e-125: 412: 27.32
+	Hs
		903302 WDR5_HUMAN (225-339): 4.64e-18: 85.5: 15.65		PKHA7_HUMAN (2-1059): 8.31e-125: 412: 27.32
+	Hs
		283021 CIAO1_HUMAN (1-337): 6.29e-105: 312: 100.00		PKHA4_HUMAN (142-851): 4.17e-38: 155: 16.85
+	Dm
		113977 GBLP_DROME (92-339): 5.66e-46: 160: 18.50		M9PB30_DROME (75-1108): 1.56e-58: 224: 10.96
+	Hs
		1318178 TBL1R_HUMAN (3-283): 1.27e-63: 211: 25.52		PKHA4_HUMAN (142-851): 4.17e-38: 155: 16.85
+	Hs
		1167395 FBXW7_HUMAN (3-217): 6.6e-46: 167: 19.73		MPRIP_HUMAN (95-395): 8.25e-38: 155: 13.86
+	Hs
		1331436 NLE1_HUMAN (226-339): 2.65e-18: 87.5: 14.91		PKHA4_HUMAN (142-851): 4.17e-38: 155: 16.85
+	Hs
		878247 SEC13_HUMAN (28-281): 8.06e-19: 87.4: 29.64		PKHA4_HUMAN (142-851): 4.17e-38: 155: 16.85
+	Hs
		903516 WDR5_HUMAN (225-339): 4.64e-18: 85.5: 15.65		PKHA4_HUMAN (142-851): 4.17e-38: 155: 16.85
+	Hs
		793030 LIS1_HUMAN (224-339): 5.41e-16: 80.1: 15.52		PKHA4_HUMAN (142-851): 4.17e-38: 155: 16.85
+	Hs
		1288303 SNR40_HUMAN (234-339): 2.57e-15: 77.8: 19.81		PKHA4_HUMAN (142-851): 4.17e-38: 155: 16.85
+	Hs
		1309164 TBL1Y_HUMAN (58-218): 5.74e-14: 74.3: 28.24		PKHA4_HUMAN (142-851): 4.17e-38: 155: 16.85
+	Hs
		1319411 WDR33_HUMAN (8-97): 1.25e-12: 70.7: 25.28		PKHA4_HUMAN (142-851): 4.17e-38: 155: 16.85
+	Hs
		197087 PRP4_HUMAN (22-180): 2.61e-09: 60.1: 28.75		PKHA4_HUMAN (142-851): 4.17e-38: 155: 16.85
+	Hs
		125310 WDR5_HUMAN (225-339): 4.64e-18: 85.5: 15.65		WWP2_HUMAN (10-213): 2.29e-27: 122: 19.51
+	Hs
		125698 WDR33_HUMAN (8-97): 1.25e-12: 70.7: 25.28		WWP2_HUMAN (10-213): 2.29e-27: 122: 19.51
+	Hs
		1264784 SNR40_HUMAN (234-339): 2.57e-15: 77.8: 19.81		TITIN_HUMAN (275-1090): 3.45e-10: 67: 9.15