HitPredict

Interactor 1: O77430 (O77430)
GEO01111p1 (HL01263p) (RH26825p) (SKP1-related A, isoform A) (SKP1-related A, isoform B) (SKP1-related A, isoform C) (SKP1-related A, isoform E) (SKP1-related A, isoform F) (SKP1-related A, isoform G) (SKPA)
Gene: SkpA

Interactor 2: CUL1 (Q24311)
Cullin homolog 1 (Lin-19 homolog protein)
Gene: CUL1

Species: Drosophila melanogaster

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.861

The method score is based on:

Property Details
Experiments 23747190, 22036573, 17099689, unassigned4
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, experimental interaction detection
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Cullin~Skp1_POZ
Common GO terms GO:0002785 - negative regulation of antimicrobial peptide production
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0016567 - protein ubiquitination
GO:0019005 - SCF ubiquitin ligase complex
and 9 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 162
Dm

1 774
+ Dm
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce
+ Hs
+ Dm
+ Sp
+ Ce
+ At
+ At
+ At
+ At
+ At
+ At
+ Hs
+ Sc
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024