HitPredict

Interactor 1: O77430 (O77430)
GEO01111p1 (HL01263p) (RH26825p) (SKP1-related A, isoform A) (SKP1-related A, isoform B) (SKP1-related A, isoform C) (SKP1-related A, isoform E) (SKP1-related A, isoform F) (SKP1-related A, isoform G) (SKPA)
Gene: SkpA

Interactor 2: Q95TK2 (Q95TK2)
Anaphase-promoting complex subunit 2
Gene: mr

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	19079254
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Cullin~Skp1_POZ
Common GO terms	GO:0045886 - negative regulation of synaptic assembly at neuromuscular junction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 162 Dm			1 449
+	Mm
		1376703 SKP1_MOUSE (1-162): 2.52e-84: 246: 76.07		CUL1_MOUSE (10-441): 9.81e-136: 410: 15.54
+	Hs
		928899 SKP1_HUMAN (1-162): 4.55e-84: 245: 76.69		CUL1_HUMAN (10-441): 9.81e-136: 410: 15.54
+	Hs
		928901 SKP1_HUMAN (1-162): 4.55e-84: 245: 76.69		CUL3_HUMAN (10-438): 3.42e-135: 408: 13.57
+	Hs
		928903 SKP1_HUMAN (1-162): 4.55e-84: 245: 76.69		CUL4B_HUMAN (8-435): 5.27e-132: 404: 15.74
+	Dm
		284976 O77430_DROME (1-162): 1.06e-83: 245: 100.00		CUL1_DROME (10-441): 1.15e-131: 399: 14.95
+	Dm
		284981 O77430_DROME (1-162): 1.06e-83: 245: 100.00		Q5BI50_DROME (8-436): 2.89e-130: 397: 15.45
+	Hs
		928902 SKP1_HUMAN (1-162): 4.55e-84: 245: 76.69		CUL4A_HUMAN (10-435): 1.59e-128: 391: 15.59
+	Hs
		929103 SKP1_HUMAN (1-162): 4.55e-84: 245: 76.69		ANC2_HUMAN (2-449): 1.35e-127: 390: 46.37
+	Hs
		928900 SKP1_HUMAN (1-162): 4.55e-84: 245: 76.69		CUL2_HUMAN (58-431): 1.41e-124: 380: 12.56
+	Dm
		1097192 Q7KJ69_DROME (1-162): 3.39e-76: 225: 72.22		CUL1_DROME (10-441): 1.15e-131: 399: 14.95
+	At
		1277333 ASK4_ARATH (4-161): 1.96e-76: 226: 47.50		CUL1_ARATH (8-438): 5.97e-128: 388: 15.03
+	At
		1277346 ASK3_ARATH (4-161): 8.12e-75: 222: 45.63		CUL1_ARATH (8-438): 5.97e-128: 388: 15.03
+	At
		1107618 SKP1A_ARATH (3-161): 1.19e-73: 219: 55.63		CUL1_ARATH (8-438): 5.97e-128: 388: 15.03
+	At
		1277329 SKP1B_ARATH (3-161): 1.45e-72: 216: 52.35		CUL1_ARATH (8-438): 5.97e-128: 388: 15.03
+	Sp
		142922 SKP1_SCHPO (1-162): 1.27e-74: 221: 56.10		CUL1_SCHPO (10-436): 3.02e-124: 380: 16.44
+	Ce
		105467 SKR1_CAEEL (4-161): 5.8e-79: 233: 63.35		CUL1_CAEEL (8-438): 3.23e-119: 367: 14.16
+	At
		221655 ASK11_ARATH (4-161): 3.57e-71: 212: 50.63		CUL1_ARATH (8-438): 5.97e-128: 388: 15.03
+	At
		1277337 ASK10_ARATH (3-161): 5.22e-69: 207: 41.88		CUL1_ARATH (8-438): 5.97e-128: 388: 15.03
+	Ce
		106724 G5EE67_CAEEL (4-161): 3.1e-68: 205: 50.31		CUL1_CAEEL (8-438): 3.23e-119: 367: 14.16
+	Ce
		106725 G5EE67_CAEEL (4-161): 3.1e-68: 205: 50.31		CUL6_CAEEL (2-438): 3.78e-105: 330: 15.30