HitPredict

Interactor 1: RSZ21 (O81127)
Serine/arginine-rich splicing factor RSZ21 (RS-containing zinc finger protein 21) (At-RSZ21) (At-RSZp21) (AtRSZ21)
Gene: RSZ21

Interactor 2: RZ22A (Q9SJA6)
Serine/arginine-rich splicing factor RSZ22A (RS-containing zinc finger protein 22A) (At-RSZ22a) (At-RSZp22a) (AtRSZ22a)
Gene: RSZ22A

Species: Arabidopsis thaliana

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.63	1.00	0.800

Property	Details
Experiments	32612234, unassigned2354
Identification Methods	two hybrid, two hybrid array, two hybrid prey pooling approach, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1, zf-CCHC~zf-CCHC
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003729 - mRNA binding GO:0005681 - spliceosomal complex GO:0008270 - zinc ion binding GO:0016607 - nuclear speck
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 187 At			1 196
+	At
		286436 RSZ21_ARATH (1-187): 4.99e-37: 128: 100.00		CYP59_ARATH (4-195): 1.64e-29: 115: 16.75
+	Zm
		41889 A0A1D6NTG8_MAIZE (1-107): 8.04e-35: 123: 69.16		A0A1D6NTG8_MAIZE (1-115): 4.24e-31: 113: 65.22
+	At
		286428 RSZ21_ARATH (1-187): 4.99e-37: 128: 100.00		RSZ21_ARATH (1-172): 8.25e-26: 99.9: 60.47
+	Hs
		432869 RBM14_HUMAN (3-187): 2.62e-26: 106: 19.27		HNRPC_HUMAN (2-196): 2e-31: 117: 16.84
+	At
		286441 RSZ21_ARATH (1-187): 4.99e-37: 128: 100.00		RSZ33_ARATH (2-144): 4.77e-21: 89.5: 32.88
+	At
		286413 RSZ22_ARATH (1-180): 7.1e-28: 105: 58.46		RSZ22_ARATH (1-196): 1.7e-28: 107: 75.12
+	At
		186859 RSZ21_ARATH (1-187): 4.99e-37: 128: 100.00		SR34_ARATH (4-81): 5.4e-17: 79: 42.68
+	Hs
		952051 ZCRB1_HUMAN (2-105): 2.98e-25: 99: 31.25		SRSF3_HUMAN (3-81): 6.02e-25: 97.2: 50.62
+	At
		1163064 CYP59_ARATH (4-171): 1.76e-26: 106: 19.15		RSZ33_ARATH (2-144): 4.77e-21: 89.5: 32.88
+	At
		286420 RSZ22_ARATH (1-180): 7.1e-28: 105: 58.46		RSZ33_ARATH (2-144): 4.77e-21: 89.5: 32.88
+	Zm
		73419 B4F7Z5_MAIZE (1-115): 1.58e-24: 97.8: 66.96		B4F7Z5_MAIZE (1-172): 8.34e-24: 96.4: 57.56
+	At
		1163070 CYP59_ARATH (4-171): 1.76e-26: 106: 19.15		SR30_ARATH (3-76): 7e-20: 86: 42.31
+	Mm
		1208011 SRSF9_MOUSE (3-177): 3.72e-25: 98.7: 24.39		RBM4_MOUSE (1-90): 6.84e-20: 87.4: 21.11
+	At
		1352382 RZ22A_ARATH (1-179): 6.02e-26: 100: 55.26		SR30_ARATH (3-76): 7e-20: 86: 42.31
+	At
		1163069 CYP59_ARATH (4-171): 1.76e-26: 106: 19.15		Q9SPI1_ARATH (4-81): 5.62e-17: 79: 42.68
+	At
		186862 CYP59_ARATH (4-171): 1.76e-26: 106: 19.15		SR34_ARATH (4-81): 5.4e-17: 79: 42.68
+	Hs
		1028598 RBM14_HUMAN (3-187): 2.62e-26: 106: 19.27		SRSF9_HUMAN (3-90): 3.72e-14: 69.8: 40.43
+	Hs
		516493 SRSF9_HUMAN (3-177): 7.67e-24: 95.3: 22.93		PABP1_HUMAN (1-83): 2.56e-16: 78.2: 27.27
+	Hs
		992750 SRSF9_HUMAN (3-177): 7.67e-24: 95.3: 22.93		SRSF1_HUMAN (3-69): 1.27e-15: 74.4: 40.85