HitPredict

Interactor 1: WBP4 (O75554)
WW domain-binding protein 4 (WBP-4) (Formin-binding protein 21) (WW domain-containing-binding protein 4)
Gene: WBP4

Interactor 2: RSMN (P63162)
Small nuclear ribonucleoprotein-associated protein N (snRNP-N) (Sm protein D) (Sm-D) (Sm protein N) (Sm-N) (SmN) (Tissue-specific-splicing protein)
Gene: SNRPN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	LSM~zf-U1
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0008380 - RNA splicing
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 376 Hs			1 240
+	Hs
		286427 WBP4_HUMAN (1-376): 3.95e-99: 300: 100.00		RSMB_HUMAN (1-168): 1.09e-43: 148: 96.43
+	Hs
		130600 WAC_HUMAN (5-345): 4.67e-63: 214: 13.75		SPT5H_HUMAN (100-228): 5e-25: 105: 17.69
+	Hs
		280482 PR40A_HUMAN (98-260): 1.45e-31: 128: 21.47		RSMB_HUMAN (1-168): 1.09e-43: 148: 96.43
+	Sc
		750253 PRP40_YEAST (126-271): 6.72e-26: 110: 21.92		RSMB_YEAST (1-165): 2.65e-36: 128: 28.72
+	Hs
		131708 WWP2_HUMAN (21-243): 7.55e-12: 69: 13.90		RSMB_HUMAN (1-168): 1.09e-43: 148: 96.43
+	At
		1274818 ZOP1_ARATH (1-80): 6.54e-23: 97.9: 40.00		Q9FI15_ARATH (1-206): 2.88e-29: 112: 47.71
+	Hs
		130300 WWP2_HUMAN (21-243): 7.55e-12: 69: 13.90		SPT5H_HUMAN (100-228): 5e-25: 105: 17.69
+	Hs
		131637 WWP2_HUMAN (21-243): 7.55e-12: 69: 13.90		SC24D_HUMAN (124-240): 5.66e-18: 84.7: 21.95