HitPredict

Interactor 1: PRKRA (O75569)
Interferon-inducible double-stranded RNA-dependent protein kinase activator A (PKR-associated protein X) (PKR-associating protein X) (Protein activator of the interferon-induced protein kinase) (Protein kinase, interferon-inducible double-stranded RNA-dependent activator)
Gene: PRKRA

Interactor 2: PRKRA (O75569)
Interferon-inducible double-stranded RNA-dependent protein kinase activator A (PKR-associated protein X) (PKR-associating protein X) (Protein activator of the interferon-induced protein kinase) (Protein kinase, interferon-inducible double-stranded RNA-dependent activator)
Gene: PRKRA

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.971

The method score is based on:

Property Details
Experiments 25416956, 16169070, 32296183, 29231267, 15358534, 21900206, 22214662, unassigned1304
Identification Methods two hybrid, affinity chromatography technology, two hybrid array, two hybrid prey pooling approach, validated two hybrid, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains dsrm~dsrm
Common GO terms GO:0003723 - RNA binding
GO:0003725 - double-stranded RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
and 26 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 313
Hs

1 313
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Service provided by Combinatics, Japan

Last updated: 11Aug2025