HitPredict

Interactor 1: LIN7C (O88952)
Protein lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3)
Gene: LIN7C

Interactor 2: KCMA1 (Q08460)
Calcium-activated potassium channel subunit alpha-1 (BK channel) (BKCA alpha) (Calcium-activated potassium channel, subfamily M subunit alpha-1) (K(VCA)alpha) (KCa1.1) (Maxi K channel) (MaxiK) (Slo-alpha) (Slo1) (mSlo1) (Slowpoke homolog) (Slo homolog) (mSlo)
Gene: Kcnma1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	19423573
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 197 Mm			1 1209
+	Gg
		1125655 LIN7C_CHICK (1-196): 6.92e-57: 179: 100.00		KCMA1_CHICK (54-1207): 0: 1340: 92.29
+	Hs
		608228 SNTB2_HUMAN (61-179): 3e-32: 123: 35.25		KCNA4_HUMAN (107-487): 6.74e-81: 280: 15.72
+	Hs
		608274 SNTA1_HUMAN (40-186): 6.39e-31: 119: 26.80		KCNA5_HUMAN (109-403): 3.51e-82: 283: 12.95
+	Hs
		159156 CSKP_HUMAN (13-194): 1.3e-30: 119: 20.53		KCNA4_HUMAN (107-487): 6.74e-81: 280: 15.72
+	Hs
		608227 SNTA1_HUMAN (40-186): 6.39e-31: 119: 26.80		KCNA4_HUMAN (107-487): 6.74e-81: 280: 15.72
+	Hs
		608229 SNTB1_HUMAN (65-179): 5.68e-31: 119: 35.90		KCNA4_HUMAN (107-487): 6.74e-81: 280: 15.72
+	Hs
		608232 MPP7_HUMAN (31-188): 6.36e-31: 119: 25.95		KCNA4_HUMAN (107-487): 6.74e-81: 280: 15.72
+	Hs
		608231 DLG2_HUMAN (23-196): 1.68e-25: 104: 23.63		KCNA4_HUMAN (107-487): 6.74e-81: 280: 15.72
+	Mm
		1143189 DLG4_MOUSE (59-195): 8.13e-24: 99.8: 26.76		KCNA6_MOUSE (137-420): 2.04e-82: 281: 15.15
+	Mm
		1142574 DLG4_MOUSE (59-195): 8.13e-24: 99.8: 26.76		KCNA4_MOUSE (107-487): 9.56e-80: 277: 15.72
+	Mm
		558878 DLG4_MOUSE (59-195): 8.13e-24: 99.8: 26.76		KCNA3_MOUSE (107-417): 7.76e-80: 274: 14.49
+	Hs
		602901 DLG4_HUMAN (59-195): 2.19e-23: 98.7: 26.76		KCNA3_HUMAN (107-417): 7.6e-80: 275: 14.76
+	Mm
		558703 DLG4_MOUSE (59-195): 8.13e-24: 99.8: 26.76		KCNA1_MOUSE (107-410): 8.57e-79: 270: 14.41
+	Mm
		927733 DLG4_MOUSE (59-195): 8.13e-24: 99.8: 26.76		KCNA2_MOUSE (107-455): 4.36e-78: 268: 13.07
+	Hs
		558713 DLG4_HUMAN (59-195): 2.19e-23: 98.7: 26.76		KCNA2_HUMAN (107-455): 6.73e-78: 267: 13.07
+	Hs
		1055046 SNTG2_HUMAN (28-188): 1.75e-32: 124: 25.77		SCN5A_HUMAN (123-325): 8.1e-16: 85.3: 12.08
+	Hs
		1033872 SNTB2_HUMAN (61-179): 3e-32: 123: 35.25		SCN5A_HUMAN (123-325): 8.1e-16: 85.3: 12.08
+	Hs
		723845 SNTA1_HUMAN (40-186): 6.39e-31: 119: 26.80		SCN1A_HUMAN (167-335): 5.87e-16: 85.7: 14.45
+	Hs
		1033834 SNTA1_HUMAN (40-186): 6.39e-31: 119: 26.80		SCN5A_HUMAN (123-325): 8.1e-16: 85.3: 12.08
+	Hs
		1046430 SNTB1_HUMAN (65-179): 5.68e-31: 119: 35.90		SCN5A_HUMAN (123-325): 8.1e-16: 85.3: 12.08