Interactor 1: PSD10 (O75832)
26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin) (p28(GANK))
Gene: PSMD10

Interactor 2: PRS8 (P62195)
26S proteasome regulatory subunit 8 (26S proteasome AAA-ATPase subunit RPT6) (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (Thyroid hormone receptor-interacting protein 1) (TRIP1) (p45/SUG)
Gene: PSMC5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.973

The method score is based on:

Property Details
Experiments 17353931, 28292943, 33961781, 35271311, 28524877, 28514442, 31839598, 19490896, unassigned3799
Identification Methods affinity chromatography technology, pull down, cross-linking study, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA_lid_3~Ank, AAA_lid_3~Ank_2
Common GO terms GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006357 - regulation of transcription by RNA polymerase II
and 1 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 226
Hs

1 406
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+ At
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Service provided by Combinatics, Japan

Last updated: 11Aug2025