Interactor 1: MTA2 (O94776)
Metastasis-associated protein MTA2 (Metastasis-associated 1-like 1) (MTA1-L1 protein) (p53 target protein in deacetylase complex)
Gene: MTA2

Interactor 2: MBD3 (O95983)
Methyl-CpG-binding domain protein 3 (Methyl-CpG-binding protein MBD3)
Gene: MBD3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.967

The method score is based on:

Property Details
Experiments 10444591, 36652389, 11297506, 19703393, 12354758, 12124384, 24981860, 25123934
Identification Methods biochemical, cross-linking study, affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type association, physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains MBD~Myb_DNA-binding
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006338 - chromatin remodeling
and 6 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 668
Hs

1 291
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Last updated: 15 Jul 2024