Protein: SC5D
Lathosterol oxidase (EC 1.14.19.20) (C-5 sterol desaturase) (Delta(7)-sterol 5-desaturase) (Delta(7)-sterol C5(6)-desaturase) (Lathosterol 5-desaturase) (Sterol-C5-desaturase)

Gene: SC5D
Organism: Homo sapiens
Interactions: 38
UniProt ID: O75845

Gene Ontology (top 5):
GO:0000248 - C-5 sterol desaturase activity
GO:0005506 - iron ion binding
GO:0005789 - endoplasmic reticulum membrane
GO:0006695 - cholesterol biosynthetic process
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

295926

BSCL2
Seipin

2

1

High-throughput

0.611

High

295914

TSN5
Tetraspanin-5

3

5

High-throughput

0.609

High

295921

S22A9
Organic anion transporter 7

3

2

High-throughput

0.604

High

295920

TPRA1
Transmembrane protein adipocyte-associated 1

2

0

High-throughput

0.602

High

295928

CML1
Chemerin-like receptor 1

2

8

High-throughput

0.601

High

295908

VIPR1
Vasoactive intestinal polypeptide receptor 1

2

3

High-throughput

0.574

High

295909

VIPR2
Vasoactive intestinal polypeptide receptor 2

2

3

High-throughput

0.574

High

295917

C3AR
C3a anaphylatoxin chemotactic receptor

2

9

High-throughput

0.574

High

295922

RL3R2
Relaxin-3 receptor 2

2

8

High-throughput

0.574

High

295923

LPAR1
Lysophosphatidic acid receptor 1

2

7

High-throughput

0.558

High

295925

TSN17
Tetraspanin-17

2

5

High-throughput

0.558

High

182435

GP182
G-protein coupled receptor 182

1

6

High-throughput

0.536

High

295907

V2R
Vasopressin V2 receptor

1

2

High-throughput

0.536

High

295904

AT1B1
Sodium/potassium-transporting ATPase subunit beta-1

1

0

High-throughput

0.513

High

295916

IDD
Integral membrane protein DGCR2/IDD

1

0

High-throughput

0.513

High

295918

LCTL
Lactase-like protein

1

0

High-throughput

0.513

High

295924

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

1

0

High-throughput

0.513

High

295900

TM63A
Mechanosensitive cation channel TMEM63A

1

2

High-throughput

0.489

High

295901

TSN15
Tetraspanin-15

1

5

High-throughput

0.489

High

295905

C5AR1
C5a anaphylatoxin chemotactic receptor 1

1

10

High-throughput

0.489

High

295906

TA2R
Thromboxane A2 receptor

1

1

High-throughput

0.489

High

295910

GPR12
G-protein coupled receptor 12

1

7

High-throughput

0.489

High

295911

P2RY1
P2Y purinoceptor 1

1

5

High-throughput

0.489

High

295930

TSN10
Tetraspanin-10

1

5

High-throughput

0.489

High

295902

RASN
GTPase NRas

1

1

High-throughput

0.479

High

295903

RASK
GTPase KRas

1

1

High-throughput

0.479

High

295931

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

2

High-throughput

0.479

High

295915

RL11
Large ribosomal subunit protein uL5

1

0

High-throughput

0.458

High

295919

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

295927

SEC62
Translocation protein SEC62

1

0

High-throughput

0.458

High

295912

S6A12
Sodium- and chloride-dependent betaine transporter

1

1

High-throughput

0.445

High

217624

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.437

High

255941

S19A2
Thiamine transporter 1

1

0

High-throughput

0.426

High

295913

CCR6
C-C chemokine receptor type 6

1

3

High-throughput

0.407

High

295929

YIPF3
Protein YIPF3

2

0

High-throughput

0.328

High

295932

IPPK
Inositol-pentakisphosphate 2-kinase

2

0

High-throughput

0.328

High

295934

PCDGL
Protocadherin gamma-C4

1

0

High-throughput

0.279

Low

295933

LZTL1
Leucine zipper transcription factor-like protein 1

1

0

High-throughput

0.269

Low


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Last updated: 11Aug2025