HitPredict

Interactor 1: STAM2 (O75886)
Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein)
Gene: STAM2

Interactor 2: UBQL2 (Q9UHD9)
Ubiquilin-2 (Chap1) (DSK2 homolog) (Protein linking IAP with cytoskeleton 2) (PLIC-2) (hPLIC-2) (Ubiquitin-like product Chap1/Dsk2)
Gene: UBQLN2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	1.00	0.843

Property	Details
Experiments	32296183, 33277362, unassigned1304
Identification Methods	two hybrid, affinity chromatography technology, validated two hybrid, two hybrid array, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	SH3_1~ubiquitin, UIM~ubiquitin, VHS~ubiquitin
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 525 Hs			1 624
+	Hs
		296591 STAM2_HUMAN (1-525): 1.05e-141: 420: 100.00		UBQL1_HUMAN (1-624): 1.17e-146: 439: 71.52
+	Hs
		1368309 STAM1_HUMAN (1-510): 4.16e-112: 345: 54.88		UBQL2_HUMAN (1-624): 1.53e-153: 457: 100.00
+	Hs
		296575 STAM2_HUMAN (1-525): 1.05e-141: 420: 100.00		UBQL4_HUMAN (22-624): 2.7e-124: 382: 54.55
+	Hs
		1256910 TM1L2_HUMAN (1-466): 1.87e-87: 280: 17.19		UBQL2_HUMAN (1-624): 1.53e-153: 457: 100.00
+	Hs
		290271 TM1L1_HUMAN (6-494): 1.97e-65: 221: 15.62		UBQL2_HUMAN (1-624): 1.53e-153: 457: 100.00
+	Hs
		1459877 GGA2_HUMAN (2-511): 2.94e-55: 197: 16.80		UBQL2_HUMAN (1-624): 1.53e-153: 457: 100.00
+	Hs
		1117527 SPTN1_HUMAN (103-481): 1.46e-55: 203: 14.59		UBQL1_HUMAN (1-624): 1.17e-146: 439: 71.52
+	Hs
		1154190 ITSN1_HUMAN (188-414): 1.92e-46: 176: 22.50		UBQL2_HUMAN (1-624): 1.53e-153: 457: 100.00
+	Hs
		169785 HGS_HUMAN (135-518): 5.13e-16: 83.2: 10.95		UBQL2_HUMAN (1-624): 1.53e-153: 457: 100.00
+	Hs
		988005 GRB2_HUMAN (207-262): 4.52e-12: 67.4: 52.63		UBQL2_HUMAN (1-624): 1.53e-153: 457: 100.00
+	Hs
		169793 HGS_HUMAN (135-518): 5.13e-16: 83.2: 10.95		UBQL1_HUMAN (1-624): 1.17e-146: 439: 71.52
+	Hs
		296483 STAM2_HUMAN (1-525): 1.05e-141: 420: 100.00		RS27A_HUMAN (33-119): 4.51e-24: 100: 27.27
+	Hs
		169766 HGS_HUMAN (135-518): 5.13e-16: 83.2: 10.95		UBQL4_HUMAN (22-624): 2.7e-124: 382: 54.55
+	Hs
		987143 STAM1_HUMAN (1-510): 4.16e-112: 345: 54.88		RS27A_HUMAN (33-119): 4.51e-24: 100: 27.27
+	Hs
		169644 HGS_HUMAN (135-518): 5.13e-16: 83.2: 10.95		UBQLN_HUMAN (5-445): 3.51e-75: 249: 33.00
+	Hs
		987319 GRB2_HUMAN (207-262): 4.52e-12: 67.4: 52.63		RL40_HUMAN (33-112): 7.23e-34: 127: 30.86
+	Hs
		986977 GRB2_HUMAN (207-262): 4.52e-12: 67.4: 52.63		RS27A_HUMAN (33-119): 4.51e-24: 100: 27.27