HitPredict

Interactor 1: HGS (O14964)
Hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) (Protein pp110)
Gene: HGS

Interactor 2: UBQL1 (Q9UMX0)
Ubiquilin-1 (Protein linking IAP with cytoskeleton 1) (PLIC-1) (hPLIC-1)
Gene: UBQLN1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.793

The method score is based on:

Property Details
Experiments 16189514, 16159959
Identification Methods two hybrid, affinity chromatography technology, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains VHS~ubiquitin
Common GO terms GO:0005829 - cytosol
GO:0016236 - macroautophagy
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 777
Hs

1 589
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Service provided by Combinatics, Japan

Last updated: 11Aug2025