HitPredict

Interactor 1: HGS (O14964)
Hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) (Protein pp110)
Gene: HGS

Interactor 2: UBQL4 (Q9NRR5)
Ubiquilin-4 (Ataxin-1 interacting ubiquitin-like protein) (A1Up) (Ataxin-1 ubiquitin-like-interacting protein A1U) (Connexin43-interacting protein of 75 kDa) (CIP75)
Gene: UBQLN4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	1.00	0.656

Property	Details
Experiments	16713569
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	VHS~ubiquitin
Common GO terms	GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 777 Hs			1 601
+	Hs
		169793 HGS_HUMAN (1-777): 1.57e-105: 343: 100.00		UBQL1_HUMAN (11-601): 1.19e-127: 389: 59.16
+	Hs
		169785 HGS_HUMAN (1-777): 1.57e-105: 343: 100.00		UBQL2_HUMAN (9-601): 6.04e-118: 365: 53.18
+	Hs
		296575 STAM2_HUMAN (4-521): 1.15e-38: 153: 14.62		UBQL4_HUMAN (1-601): 6.43e-143: 429: 100.00
+	Hs
		169644 HGS_HUMAN (1-777): 1.57e-105: 343: 100.00		UBQLN_HUMAN (14-459): 9.62e-60: 208: 29.39
+	Hs
		1256910 TM1L2_HUMAN (5-448): 7.23e-50: 185: 17.17		UBQL2_HUMAN (9-601): 6.04e-118: 365: 53.18
+	Hs
		296591 STAM2_HUMAN (4-521): 1.15e-38: 153: 14.62		UBQL1_HUMAN (11-601): 1.19e-127: 389: 59.16
+	Hs
		1368309 STAM1_HUMAN (4-172): 1.4e-42: 164: 28.40		UBQL2_HUMAN (9-601): 6.04e-118: 365: 53.18
+	Hs
		296589 STAM2_HUMAN (4-521): 1.15e-38: 153: 14.62		UBQL2_HUMAN (9-601): 6.04e-118: 365: 53.18
+	Hs
		290271 TM1L1_HUMAN (5-474): 1.09e-35: 143: 14.32		UBQL2_HUMAN (9-601): 6.04e-118: 365: 53.18
+	Hs
		336077 ZFYV9_HUMAN (155-539): 2.26e-38: 156: 19.00		BAG6_HUMAN (2-547): 7.23e-64: 229: 13.41
+	At
		306625 TOL6_ARATH (13-146): 6.14e-40: 158: 37.78		UBQ3_ARATH (9-88): 9.71e-33: 129: 30.86
+	At
		1168316 Q9SRZ7_ARATH (149-508): 5.37e-39: 157: 19.38		UBQ3_ARATH (9-88): 9.71e-33: 129: 30.86
+	At
		1167951 TOL5_ARATH (8-340): 8.36e-38: 148: 16.91		UBQ3_ARATH (9-88): 9.71e-33: 129: 30.86
+	Hs
		987143 STAM1_HUMAN (4-172): 1.4e-42: 164: 28.40		RS27A_HUMAN (13-99): 1.12e-12: 68.1: 29.55
+	Hs
		987091 ZFY16_HUMAN (137-496): 3.67e-38: 155: 17.80		RS27A_HUMAN (13-99): 1.12e-12: 68.1: 29.55
+	Hs
		296483 STAM2_HUMAN (4-521): 1.15e-38: 153: 14.62		RS27A_HUMAN (13-99): 1.12e-12: 68.1: 29.55