HitPredict

Interactor 1: TOX4 (O94842)
TOX high mobility group box family member 4 (Epidermal Langerhans cell protein LCP1)
Gene: TOX4

Interactor 2: TYY1 (P25490)
Transcriptional repressor protein YY1 (Delta transcription factor) (INO80 complex subunit S) (NF-E1) (Yin and yang 1) (YY-1)
Gene: YY1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 621 Hs			1 414
+	Hs
		632942 HMGX4_HUMAN (55-335): 2.61e-40: 157: 20.41		TYY1_HUMAN (1-414): 1.26e-138: 404: 100.00
+	Hs
		632642 SOX2_HUMAN (185-480): 3.81e-31: 125: 13.61		TYY1_HUMAN (1-414): 1.26e-138: 404: 100.00
+	Hs
		449547 HMGB1_HUMAN (139-302): 5.39e-28: 113: 20.23		TYY1_HUMAN (1-414): 1.26e-138: 404: 100.00
+	Mm
		818696 SOX2_MOUSE (186-480): 7.81e-30: 121: 13.02		TYY1_MOUSE (1-414): 7.48e-133: 389: 94.23
+	Hs
		617245 SP100_HUMAN (164-303): 3.95e-21: 100: 24.83		TYY1_HUMAN (1-414): 1.26e-138: 404: 100.00
+	Hs
		818499 SOX2_HUMAN (185-480): 3.81e-31: 125: 13.61		ZNF71_HUMAN (36-348): 2.24e-86: 273: 15.95
+	Hs
		818150 SOX2_HUMAN (185-480): 3.81e-31: 125: 13.61		ZN787_HUMAN (303-411): 4.94e-21: 95.9: 47.27
+	Hs
		563474 SSRP1_HUMAN (148-386): 3.7e-29: 124: 18.11		ZNF22_HUMAN (303-382): 2.37e-12: 67.8: 41.98