HitPredict

Interactor 1: PIAS1 (O75925)
E3 SUMO-protein ligase PIAS1 (EC 2.3.2.-) (DEAD/H box-binding protein 1) (E3 SUMO-protein transferase PIAS1) (Gu-binding protein) (GBP) (Protein inhibitor of activated STAT protein 1) (RNA helicase II-binding protein)
Gene: PIAS1

Interactor 2: TACC3 (Q9Y6A5)
Transforming acidic coiled-coil-containing protein 3 (ERIC-1)
Gene: TACC3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	40437099
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 651 Hs			1 838
+	Hs
		297662 PIAS1_HUMAN (1-651): 0: 874: 100.00		CBP_HUMAN (5-587): 6.87e-41: 165: 11.52
+	Hs
		297589 PIAS1_HUMAN (1-651): 0: 874: 100.00		EP300_HUMAN (14-587): 4.28e-20: 98.4: 8.29
+	Hs
		270746 PIAS1_HUMAN (1-651): 0: 874: 100.00		ROCK2_HUMAN (401-837): 2.39e-13: 76.5: 9.87
+	Hs
		297479 PIAS1_HUMAN (1-651): 0: 874: 100.00		MYH10_HUMAN (588-838): 1.09e-11: 71: 13.39
+	Hs
		1368547 PIAS3_HUMAN (1-651): 0: 740: 56.88		CBP_HUMAN (5-587): 6.87e-41: 165: 11.52
+	Hs
		1067895 PIAS3_HUMAN (1-651): 0: 740: 56.88		EP300_HUMAN (14-587): 4.28e-20: 98.4: 8.29
+	Hs
		297844 PIAS2_HUMAN (1-566): 0: 633: 58.97		CBP_HUMAN (5-587): 6.87e-41: 165: 11.52