Interactor 1: TRIO (O75962)
Triple functional domain protein (EC 2.7.11.1) (PTPRF-interacting protein)
Gene: TRIO
Interactor 2: PTPRS (Q13332)
Receptor-type tyrosine-protein phosphatase S (R-PTP-S) (EC 3.1.3.48) (Receptor-type tyrosine-protein phosphatase sigma) (R-PTP-sigma)
Gene: PTPRS
Species: Homo sapiens
Source: biogrid
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 27880917 |
| Identification Methods | proximity labelling technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | I-set~fn3, I-set~I-set, I-set~Ig_3, Pkinase~fn3, I-set~Pkinase, RhoGEF~fn3, SOS1_NGEF_PH~fn3 |
| Common GO terms | GO:0005829 - cytosol GO:0098978 - glutamatergic synapse |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
