HitPredict

Interactor 1: GLRX3 (O76003)
Glutaredoxin-3 (PKC-interacting cousin of thioredoxin) (PICOT) (PKC-theta-interacting protein) (PKCq-interacting protein) (Thioredoxin-like protein 2)
Gene: GLRX3

Interactor 2: IGF1R (P08069)
Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]
Gene: IGF1R

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	34591642
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 335 Hs			1 1367
+	Hs
		439791 TXND5_HUMAN (6-323): 5.46e-51: 176: 15.30		INSR_HUMAN (32-1365): 0: 1242: 56.39
+	Hs
		439738 PDIA6_HUMAN (1-251): 9.7e-38: 141: 14.78		INSR_HUMAN (32-1365): 0: 1242: 56.39
+	Rn
		580528 PDIA6_RAT (1-251): 7.89e-39: 144: 15.12		INSR_RAT (4-1365): 0: 1233: 55.19
+	Hs
		572945 TXND5_HUMAN (6-323): 5.46e-51: 176: 15.30		INSRR_HUMAN (14-1310): 0: 1192: 55.18
+	Rn
		547733 PDIA3_RAT (1-137): 5.06e-28: 115: 18.18		INSR_RAT (4-1365): 0: 1233: 55.19
+	Rn
		415183 PDIA1_RAT (1-144): 9.66e-25: 106: 18.00		INSR_RAT (4-1365): 0: 1233: 55.19
+	At
		87689 TRXH3_ARATH (8-117): 2.06e-37: 131: 28.57		Y1756_ARATH (487-1285): 0: 615: 15.78
+	At
		1192538 TRXH3_ARATH (8-117): 2.06e-37: 131: 28.57		Y5188_ARATH (430-1304): 0: 599: 15.88
+	At
		88347 TRXH5_ARATH (27-122): 1.19e-38: 135: 31.25		Y2289_ARATH (541-1298): 0: 574: 14.56
+	At
		87643 TRXH5_ARATH (27-122): 1.19e-38: 135: 31.25		Y1755_ARATH (432-1291): 0: 571: 15.92
+	Hs
		300091 GLRX3_HUMAN (18-335): 2.19e-104: 310: 100.00		NTRK1_HUMAN (977-1262): 3.03e-70: 254: 42.61
+	Hs
		412267 TXND5_HUMAN (6-323): 5.46e-51: 176: 15.30		NTRK1_HUMAN (977-1262): 3.03e-70: 254: 42.61
+	Hs
		720276 TXND5_HUMAN (6-323): 5.46e-51: 176: 15.30		UFO_HUMAN (790-1271): 9.31e-68: 249: 32.10
+	Hs
		1142430 PDIA6_HUMAN (1-251): 9.7e-38: 141: 14.78		ALK_HUMAN (939-1304): 2.53e-75: 278: 39.12
+	Hs
		411965 PDIA6_HUMAN (1-251): 9.7e-38: 141: 14.78		NTRK1_HUMAN (977-1262): 3.03e-70: 254: 42.61
+	Hs
		215236 TXNL1_HUMAN (12-258): 4.17e-38: 139: 20.08		NTRK1_HUMAN (977-1262): 3.03e-70: 254: 42.61
+	Hs
		411246 THIO_HUMAN (13-116): 3.63e-37: 130: 26.92		NTRK1_HUMAN (977-1262): 3.03e-70: 254: 42.61
+	Hs
		1142279 PDIA6_HUMAN (1-251): 9.7e-38: 141: 14.78		NTRK3_HUMAN (977-1262): 5.77e-64: 236: 39.16
+	Hs
		411281 PDIA4_HUMAN (1-115): 3e-24: 105: 19.67		NTRK1_HUMAN (977-1262): 3.03e-70: 254: 42.61
+	Hs
		528189 THIO_HUMAN (13-116): 3.63e-37: 130: 26.92		ERBB3_HUMAN (15-362): 5.24e-33: 141: 20.05