HitPredict

Interactor 1: SC31A (O94979)
Protein transport protein Sec31A (ABP125) (ABP130) (SEC31-like protein 1) (SEC31-related protein A) (Web1-like protein)
Gene: SEC31A

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	27716508, 35120648, 21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1220 Hs			1 768
+	Hs
		997713 RBBP4_HUMAN (9-349): 7.97e-83: 279: 17.49		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		903207 WDR5_HUMAN (206-522): 2.88e-60: 212: 14.95		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042655 NLE1_HUMAN (243-545): 1.47e-43: 168: 10.29		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		725432 COPB2_HUMAN (1-243): 1.76e-41: 167: 12.30		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		997714 RBBP4_HUMAN (9-349): 7.97e-83: 279: 17.49		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		997715 RBBP4_HUMAN (9-349): 7.97e-83: 279: 17.49		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		1041672 RBBP7_HUMAN (17-155): 1.09e-16: 86: 14.19		CUL3_HUMAN (1-768): 0: 951: 100.00
+	At
		186930 MSI1_ARATH (9-351): 3.39e-80: 271: 16.28		CUL4_ARATH (8-768): 0: 744: 38.61
+	Hs
		1043562 TBL1R_HUMAN (17-335): 7.88e-65: 231: 15.51		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		903208 WDR5_HUMAN (206-522): 2.88e-60: 212: 14.95		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		903209 WDR5_HUMAN (206-522): 2.88e-60: 212: 14.95		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		245601 TBL1X_HUMAN (118-461): 1.88e-53: 199: 15.70		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		1043085 WDR5B_HUMAN (1-244): 1.46e-50: 183: 12.96		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		1043441 WDR5B_HUMAN (1-244): 1.46e-50: 183: 12.96		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		903206 WDR5_HUMAN (206-522): 2.88e-60: 212: 14.95		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Hs
		1043016 RBBP7_HUMAN (17-155): 1.09e-16: 86: 14.19		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		792982 LIS1_HUMAN (331-619): 6.2e-16: 83.4: 7.74		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		1043376 RBBP7_HUMAN (17-155): 1.09e-16: 86: 14.19		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Ce
		953926 LIN53_CAEEL (167-432): 5.15e-40: 155: 14.04		CUL1_CAEEL (16-768): 0: 647: 26.01
+	Ce
		953927 LIN53_CAEEL (167-432): 5.15e-40: 155: 14.04		CUL2_CAEEL (30-768): 0: 613: 24.10