HitPredict

Interactor 1: RTN3 (O95197)
Reticulon-3 (Homolog of ASY protein) (HAP) (Neuroendocrine-specific protein-like 2) (NSP-like protein 2) (Neuroendocrine-specific protein-like II) (NSP-like protein II) (NSPLII)
Gene: RTN3

Interactor 2: GPR35 (Q9HC97)
G-protein coupled receptor 35 (Kynurenic acid receptor) (KYNA receptor)
Gene: GPR35

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	28298427, 33961781
Identification Methods	two hybrid, affinity chromatography technology, ubiquitin reconstruction, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1032 Hs			1 309
+	Hs
		306990 RTN3_HUMAN (1-1032): 0: 645: 100.00		CCR2_HUMAN (9-297): 1.92e-66: 214: 18.94
+	Hs
		306986 RTN3_HUMAN (1-1032): 0: 645: 100.00		AGTR1_HUMAN (10-309): 9.54e-62: 201: 21.12
+	Hs
		1343291 RTN4_HUMAN (64-1030): 9.26e-60: 225: 21.16		CLTR2_HUMAN (2-293): 1.29e-77: 242: 26.32
+	Hs
		1335878 RTN4_HUMAN (64-1030): 9.26e-60: 225: 21.16		GPR35_HUMAN (1-309): 5.97e-71: 223: 100.00
+	Hs
		849639 RTN4_HUMAN (64-1030): 9.26e-60: 225: 21.16		CCR4_HUMAN (9-295): 1.33e-62: 203: 20.53
+	Hs
		666351 RTN4_HUMAN (64-1030): 9.26e-60: 225: 21.16		NK3R_HUMAN (7-294): 1.51e-60: 201: 18.89
+	Hs
		429058 RTN1_HUMAN (271-1028): 2.29e-45: 178: 22.73		ADRB2_HUMAN (2-307): 8.28e-67: 216: 14.33
+	Hs
		849627 RTN1_HUMAN (271-1028): 2.29e-45: 178: 22.73		CCR4_HUMAN (9-295): 1.33e-62: 203: 20.53
+	Hs
		798455 RTN4_HUMAN (64-1030): 9.26e-60: 225: 21.16		LPAR6_HUMAN (27-286): 4.94e-34: 129: 30.61