HitPredict

Interactor 1: RPA1 (O95602)
DNA-directed RNA polymerase I subunit RPA1 (RNA polymerase I subunit A1) (EC 2.7.7.6) (A190) (DNA-directed RNA polymerase I largest subunit) (DNA-directed RNA polymerase I subunit A) (RNA polymerase I 194 kDa subunit) (RPA194)
Gene: POLR1A

Interactor 2: RRN3 (Q9NYV6)
RNA polymerase I-specific transcription initiation factor RRN3 (Transcription initiation factor IA) (TIF-IA)
Gene: RRN3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	1.00	0.881

Property	Details
Experiments	26496610, 11250903, 33961781, 19214185
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RNA_pol_Rpb1_2~RRN3
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 1720 Hs			1 651
+	Hs
		99498 RPA1_HUMAN (1-1720): 0: 1954: 100.00		F5H148_HUMAN (1-651): 0: 861: 95.39
+	Sc
		501355 RPA1_YEAST (3-1719): 0: 1494: 35.97		RRN3_YEAST (55-587): 1.3e-156: 467: 23.31