HitPredict

Interactor 1: PCNT (O95613)
Pericentrin (Kendrin) (Pericentrin-B)
Gene: PCNT

Interactor 2: DYL1 (P63167)
Dynein light chain 1, cytoplasmic (8 kDa dynein light chain) (DLC8) (Dynein light chain LC8-type 1) (Protein inhibitor of neuronal nitric oxide synthase) (PIN)
Gene: DYNLL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005829 - cytosol GO:0005874 - microtubule GO:0016020 - membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 3336 Hs			1 89
+	Hs
		317324 PCNT_HUMAN (1-3336): 0: 718: 100.00		DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26
+	Hs
		928303 NUMA1_HUMAN (43-1227): 1.53e-33: 145: 10.92		DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00
+	Hs
		928445 AKAP9_HUMAN (1605-3329): 1.28e-32: 142: 9.38		DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00
+	Hs
		1291284 AKAP9_HUMAN (1605-3329): 1.28e-32: 142: 9.38		DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26
+	Hs
		928301 GOGB1_HUMAN (2204-3322): 8.52e-25: 117: 9.50		DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00
+	Hs
		1059254 GOGB1_HUMAN (2204-3322): 8.52e-25: 117: 9.50		DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26
+	Dm
		114783 M9PD87_DROME (214-964): 7.73e-10: 67.6: 15.67		DYL1_DROME (1-89): 1.36e-46: 145: 94.38
+	Dm
		1096053 Q9VKI0_DROME (214-964): 1.57e-09: 66.5: 15.67		DYL1_DROME (1-89): 1.36e-46: 145: 94.38
+	Hs
		1189784 MYH14_HUMAN (1365-1911): 6.08e-09: 64.6: 17.69		DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26